Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.64 |
| ▸ | S1PR3 | Q99500 | 13/20 | 0.64 |
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16130241 | 0.94 | S1PR1 (0.64) | S1PR1S1PR3CFTR | |
| SCHEMBL944206 | 0.86 | S1PR3 (0.69) | S1PR1S1PR3 | |
| SCHEMBL17295464 | 0.85 | CA9 (0.65) | S1PR1S1PR3CFTRCA9DYRK3 | |
| SCHEMBL17295466 | 0.85 | CA9 (0.65) | S1PR1S1PR3CFTRCA9DYRK3 | |
| SCHEMBL12912689 | 0.85 | S1PR1 (0.61) | S1PR1S1PR3DYRK3DYRK2CSNK2A2 | |
| SCHEMBL16130327 | 0.84 | S1PR1 (0.66) | S1PR1S1PR3CFTRCA9DYRK3 | |
| SCHEMBL16130335 | 0.84 | S1PR1 (0.66) | S1PR1S1PR3CFTRCA9DYRK3 | |
| SCHEMBL12912690 | 0.84 | S1PR1 (0.59) | S1PR1S1PR3DYRK1ADYRK1B | |
| SCHEMBL16130331 | 0.82 | S1PR1 (0.67) | S1PR1S1PR3CFTRCA9DYRK3 | |
| SCHEMBL16503659 | 0.81 | MAPK1 (0.61) | KMT2ACSNK2A2CSNK2BCSNK2A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE45174-E1 | Thiazolidin-4-one derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2014-09-30 | — | — | US | disclosed |