Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 17/20 | 0.64 |
| ▸ | S1PR3 | Q99500 | 17/20 | 0.64 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16130242 | 0.94 | S1PR1 (0.64) | S1PR1S1PR3CFTR | |
| SCHEMBL12912689 | 0.89 | S1PR1 (0.61) | S1PR1S1PR3FAAH | |
| SCHEMBL12912690 | 0.88 | S1PR1 (0.59) | S1PR1S1PR3FAAH | |
| SCHEMBL16130240 | 0.86 | S1PR1 (0.64) | S1PR1S1PR3CFTRGSK3BFAAH | |
| SCHEMBL944429 | 0.86 | S1PR3 (0.69) | S1PR1S1PR3 | |
| SCHEMBL17302145 | 0.85 | MEN1 (0.62) | S1PR1S1PR3GSK3BFAAH | |
| SCHEMBL16130328 | 0.84 | S1PR1 (0.66) | S1PR1S1PR3CFTR | |
| SCHEMBL16130254 | 0.84 | S1PR1 (0.66) | S1PR1S1PR3CFTRGSK3B | |
| SCHEMBL17295538 | 0.83 | FAAH (0.57) | S1PR1S1PR3FAAH | |
| SCHEMBL17295539 | 0.83 | FAAH (0.57) | S1PR1S1PR3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE45174-E1 | Thiazolidin-4-one derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2014-09-30 | — | — | US | disclosed |