Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.65 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.65 |
| ▸ | CFTR | P13569 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16130325 | 0.94 | S1PR1 (0.65) | S1PR1S1PR3CFTRKMT2AMITF | |
| SCHEMBL12912717 | 0.86 | CFTR (0.66) | S1PR1S1PR3CFTRKMT2AMITF | |
| SCHEMBL12912678 | 0.85 | S1PR1 (0.62) | S1PR1S1PR3CFTRKMT2AMAPK1 | |
| SCHEMBL12912676 | 0.84 | S1PR1 (0.60) | S1PR1S1PR3CFTRKMT2AMAPK1 | |
| SCHEMBL20005672 | 0.81 | MAPK1 (0.72) | CFTRKMT2AMITFMAPK1MAPT | |
| SCHEMBL18103053 | 0.81 | MAPK1 (0.72) | CFTRKMT2AMITFMAPK1MAPT | |
| SCHEMBL16130282 | 0.80 | TDP1 (0.65) | S1PR1S1PR3CFTRKMT2AMITF | |
| SCHEMBL944206 | 0.79 | S1PR3 (0.69) | S1PR1S1PR3 | |
| SCHEMBL12912633 | 0.78 | MEN1 (0.74) | S1PR1S1PR3KMT2AMAPK1CA9 | |
| SCHEMBL16130306 | 0.78 | S1PR1 (0.65) | S1PR1S1PR3CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE45174-E1 | Thiazolidin-4-one derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2014-09-30 | — | — | US | disclosed |