Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.57 |
| ▸ | ITGAV | P06756 | 16/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.57 |
| ▸ | ITGB5 | P18084 | 10/20 | 0.55 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.52 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.52 |
| ▸ | ITGB8 | P26012 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366713 | 0.87 | ITGB3 (0.74) | ITGB3ITGAVITGA2BITGB5ITGA5 | |
| SCHEMBL17364341 | 0.87 | ITGB3 (0.74) | ITGB3ITGAVITGA2BITGB5ITGA5 | |
| SCHEMBL7743709 | 0.87 | ITGB3 (0.58) | ITGB3ITGAVITGA2BITGB5ITGA5 | |
| SCHEMBL13166793 | 0.87 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB5ITGA5 | |
| SCHEMBL16435343 | 0.86 | ITGB3 (0.54) | ITGB3ITGAVITGA2BITGB5ITGA5 | |
| SCHEMBL16349548 | 0.86 | ITGB3 (0.50) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL10259650 | 0.86 | MC4R (0.62) | ITGB3ITGAVITGA2BITGB5ITGA5 | |
| SCHEMBL12808284 | 0.86 | ITGB3 (0.55) | ITGB3ITGAVITGA2BITGB5ITGA5 | |
| SCHEMBL14885799 | 0.86 | ITGB3 (0.55) | ITGB3ITGAVITGA2BITGB5ITGA5 | |
| SCHEMBL21475019 | 0.86 | ITGB3 (0.55) | ITGB3ITGAVITGA2BITGB5ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846110-B2 | Polymeric systems for the delivery of anticancer drugs | REXAHN PHARMACEUTICALS, INC. (US) | 2014-09-30 | — | — | US | disclosed |