Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16132406 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1CHRM3KCNA5KCNJ5 | |
| SCHEMBL16132342 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1CHRM3KCNA5KCNJ5 | |
| SCHEMBL17490338 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1CHRM3KCNA5AHR | |
| SCHEMBL18635601 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1CHRM3KCNA5AHR | |
| SCHEMBL17487253 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1CHRM3AHRCHRM2 | |
| SCHEMBL16132426 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1CHRM3KCNA5AHR | |
| SCHEMBL16132485 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1CHRM3KCNA5AHR | |
| SCHEMBL17490349 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1CHRM3KCNA5AHR | |
| SCHEMBL17490360 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1CHRM3KCNA5AHR | |
| SCHEMBL16132343 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1CHRM3KCNA5AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255089-B2 | Benzimidazolone derivatives as bromodomain inhibitors | GILEAD SCIENCES, INC. (US) | 2016-02-09 | — | — | US | disclosed |
| US-20140296246-A1 | BENZIMIDAZOLONE DERIVATIVES AS BROMODOMAIN INHIBITORS | GILEAD SCIENCES, INC. (US) | 2014-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296246-A1 | BENZIMIDAZOLONE DERIVATIVES AS BROMODOMAIN INHIBITORS | BRD4, BRD3, BRD1 | SMN1; SMN2 3186/4885L3MBTL1 1346/4885CHRM3 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.