SCHEMBL1613299

SCHEMBL1613299

[C-]#[N+]c1cnn(-c2c(Cl)cccc2Cl)c1N=Nc1c(C)nn(-c2nc(O)nc(-n3nc(C)c(N=Nc4c(C#N)cnn4-c4c(Cl)cccc4Cl)c3N)n2)c1N

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.33
MAPT P10636 4/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
TDP1 Q9NUW8 3/20 0.33
MEN1 O00255 2/20 0.33
MAPK1 P28482 2/20 0.33
ALOX12 P18054 1/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GLA P06280 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10052061 0.93 MAPT (0.38) KMT2AMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL1613303 0.88 SMN1; SMN2 (0.41) KMT2AMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL10194314 0.85 MAPT (0.40) KMT2AMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL1613519 0.84 SMN1; SMN2 (0.44) KMT2AMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL1613194 0.83 KMT2A (0.35) KMT2AMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL10194391 0.83 MAPT (0.37) KMT2AMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL1611699 0.83 MAPT (0.37) KMT2AMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL1612905 0.82
SCHEMBL10194305 0.82 SMN1; SMN2 (0.42) KMT2AMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL10139559 0.81 XDH (0.36) KMT2AMAPTNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8808440-B2 Ink composition, ink for inkjet recording and inkjet recording method FUJIFILM CORPORATION (JP) 2014-08-19 US disclosed
US-8399664-B2 Coloring matter, ink, ink for ink jet, ink jet recording method, color toner, and color filter FUJIFILM CORPORATION (JP) 2013-03-19 US disclosed
US-8357235-B2 Inkjet ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2013-01-22 US disclosed
US-8262789-B2 Coloring matter, ink, ink for ink jet, ink jet recording method, color toner, and color filter FUJIFILM CORPORATION (JP) 2012-09-11 US disclosed
US-20120095194-A1 COLORING MATTER, INK, INK FOR INK JET, INK JET RECORDING METHOD, COLOR TONER, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2012-04-19 US disclosed
US-20120095195-A1 COLORING MATTER, INK, INK FOR INK JET, INK JET RECORDING METHOD, COLOR TONER, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2012-04-19 US disclosed
US-20120088910-A1 COLORING MATTER, INK, INK FOR INK JET, INK JET RECORDING METHOD, COLOR TONER, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2012-04-12 US disclosed
US-8101011-B2 Mono- and diazo dyes including pyrazol-5-yl rings attached to the azo group; good shades (hues) in the primary colors; colorfastness; photostability; weatherproofing; heat resistance; waterproofing; oxidation/ozone resistance; chemical resistance; storage stability; printing;electrography; displays FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20100242791-A1 INKJET INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
US-20100231670-A1 SET FOR INK JET RECORDING, AND INK JET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-09-16 US disclosed
US-7758683-B2 Ink composition, ink set and recording method FUJIFILM CORPORATION (JP) 2010-07-20 US disclosed
US-7704311-B2 Ink composition, manufacturing method of ink, ink set, and recording method FUJIFILM CORPORATION (JP) 2010-04-27 US disclosed
US-20100075041-A1 INKJET RECORDING YELLOW INK, INKJET RECORDING INK SET AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
US-20100071588-A1 INKJET RECORDING YELLOW INK, INKJET RECORDING INK SET AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
US-20090246378-A1 Ink composition, ink set, and image recording method FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20080274283-A1 Coloring Matter, Ink, Ink, for Ink Jet, Ink Jet Recording Method, Color Toner, and Color Filter FUJIFILM CORPORATION (JP) 2008-11-06 US disclosed
US-20070109376-A1 Ink composition, ink set and recording method FUJIFILM CORPORATION 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088910-A1 COLORING MATTER, INK, INK FOR INK JET, INK JET RECORDING METHOD, COLOR TONER, AND COLOR FILTER H1-5, IK, H1-2 KMT2A 222/4885MAPT 1984/4885NPC1 3929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.