SCHEMBL16133175

SCHEMBL16133175

c1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cccc(-c3ccc4c(c3)c3cccc5c6ccccc6c6cccc4c6c53)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 1/20 0.47
TSPO P30536 3/20 0.40
ALDH1A1 P00352 2/20 0.36
HTT P42858 2/20 0.36
FAAH O00519 1/20 0.36
HSP90AA1 P07900 1/20 0.36
PKM P14618 1/20 0.36
MGLL Q99685 1/20 0.36
HTR1A P08908 1/20 0.35
HTR7 P34969 1/20 0.35
KMT2A Q03164 2/20 0.35
IL1R1 P14778 1/20 0.35
HDAC4 P56524 1/20 0.34
DNM1 Q05193 1/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
NR4A2 P43354 1/20 0.34
RXRA P19793 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16303803 0.96 ATM (0.52) ATML3MBTL1KDM4ETSPOALDH1A1
SCHEMBL16373514 0.96 ATM (0.52) ATML3MBTL1KDM4ETSPOALDH1A1
SCHEMBL15479938 0.96 ATM (0.52) ATML3MBTL1KDM4ETSPOALDH1A1
SCHEMBL15479810 0.94 ATM (0.45) ATML3MBTL1KDM4ETSPOALDH1A1
SCHEMBL16133171 0.94 ATM (0.47) ATML3MBTL1KDM4ETSPOALDH1A1
SCHEMBL21034923 0.94 L3MBTL1 (0.55) ATML3MBTL1KDM4ETSPOALDH1A1
SCHEMBL21034876 0.94 L3MBTL1 (0.55) ATML3MBTL1KDM4ETSPOALDH1A1
SCHEMBL19474309 0.94 ATM (0.50) ATML3MBTL1KDM4ETSPOALDH1A1
SCHEMBL16566427 0.94 ATM (0.50) ATML3MBTL1KDM4ETSPOALDH1A1
SCHEMBL16089795 0.94 ATM (0.50) ATML3MBTL1KDM4ETSPOALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed