SCHEMBL16133238

SCHEMBL16133238

c1cc(-c2ccc3c4ccccc4c4cc5c6ccccc6c6ccccc6c5cc4c3c2)nc(-c2cccc3c2sc2ccccc23)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.50
PARP14 Q460N5 1/20 0.39
PRKDC P78527 8/20 0.38
MAPT P10636 2/20 0.38
PIM1 P11309 2/20 0.37
PIM3 Q86V86 2/20 0.37
PIM2 Q9P1W9 2/20 0.37
PIK3CD O00329 2/20 0.35
PIK3CB P42338 2/20 0.35
F9 P00740 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GPR3 P46089 1/20 0.34
BRD4 O60885 1/20 0.34
PIK3CA P42336 1/20 0.34
MTOR P42345 1/20 0.34
PIK3CG P48736 1/20 0.34
KCNH2 Q12809 1/20 0.34
BRDT Q58F21 1/20 0.34
RAB9A P51151 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12175628 0.99 ALOX5 (0.51) ALOX5PARP14PRKDCMAPTPIM1
SCHEMBL16133197 0.95 ALOX5 (0.48) ALOX5PARP14PRKDCMAPTPIM1
SCHEMBL12175670 0.95 ALOX5 (0.48) ALOX5PARP14PRKDCMAPTPIM1
SCHEMBL15582064 0.88 ALOX5 (0.47) ALOX5PARP14PRKDCMAPTPIK3CD
SCHEMBL16133186 0.86 ALOX5 (0.47) ALOX5PARP14PRKDCMAPTPIM1
SCHEMBL9891018 0.85 ALOX5 (0.51) ALOX5PARP14PRKDCMAPTPIK3CD
SCHEMBL15294173 0.84 ALOX5 (0.40) ALOX5PARP14PRKDCMAPTPIM1
SCHEMBL16133224 0.84 ALOX5 (0.68) ALOX5PARP14PRKDCMAPTPIK3CD
SCHEMBL20698071 0.84 ALOX5 (0.68) ALOX5PARP14PRKDCMAPTPIK3CD
SCHEMBL16133228 0.84 ALOX5 (0.68) ALOX5PARP14PRKDCMAPTPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed