SCHEMBL16133258

SCHEMBL16133258

c1ccc2c(c1)oc1c(-c3ccc4c(c3)c3cccc5c6ccccc6c6cccc4c6c53)cccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.64
PRKDC P78527 5/20 0.49
GGPS1 O95749 1/20 0.47
PTGES2 Q9H7Z7 1/20 0.44
CDC25A P30304 1/20 0.39
CDC25B P30305 1/20 0.39
CDC25C P30307 1/20 0.39
ATM Q13315 1/20 0.39
AHR P35869 2/20 0.38
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
PIK3CD O00329 1/20 0.37
PIK3CB P42338 1/20 0.37
MEN1 O00255 2/20 0.37
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
DYRK1A Q13627 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21035455 1.00 ALOX5 (0.64) ALOX5PRKDCGGPS1PTGES2CDC25A
SCHEMBL21035456 1.00 ALOX5 (0.64) ALOX5PRKDCGGPS1PTGES2CDC25A
SCHEMBL13615935 0.97 ALOX5 (0.64) ALOX5PRKDCGGPS1PTGES2CDC25A
SCHEMBL13615747 0.97 ALOX5 (0.64) ALOX5PRKDCGGPS1PTGES2CDC25A
SCHEMBL13615905 0.97 ALOX5 (0.64) ALOX5PRKDCGGPS1PTGES2CDC25A
SCHEMBL16133244 0.96 ALOX5 (0.59) ALOX5PRKDCGGPS1PTGES2CDC25A
SCHEMBL13615865 0.95 ALOX5 (0.66) ALOX5PRKDCGGPS1PTGES2CDC25A
SCHEMBL14924577 0.95 ALOX5 (0.69) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL12175683 0.95 ALOX5 (0.69) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL16302998 0.95 ALOX5 (0.69) ALOX5PRKDCGGPS1PTGES2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed