Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20112900 | 0.84 | ATM (0.46) | ALDH1A1KDM4EATMEPHX1TLR4 | |
| SCHEMBL24449811 | 0.84 | ATM (0.46) | ALDH1A1KDM4EATMEPHX1TLR4 | |
| SCHEMBL24448966 | 0.84 | HPGD (0.41) | EPHX1SMN1; SMN2GAARAB9AHPGD | |
| SCHEMBL24449510 | 0.84 | EPHX1 (0.44) | ALDH1A1KDM4EATMEPHX1SMN1; SMN2 | |
| SCHEMBL24449443 | 0.81 | EPHX1 (0.49) | ALDH1A1KDM4EEPHX1KMT2A | |
| SCHEMBL24724954 | 0.81 | EPHX1 (0.49) | ALDH1A1KDM4EEPHX1KMT2A | |
| SCHEMBL12424257 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4EATMEPHX1TLR4 | |
| SCHEMBL23081205 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4EATMEPHX1TLR4 | |
| SCHEMBL2450437 | 0.80 | GRM5 (0.45) | SMN1; SMN2RAB9AHPGDKMT2ACA12 | |
| SCHEMBL25117765 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EATMEPHX1TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140296201-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED | 2014-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296201-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | ACE, IRF3, ACE2 | ALDH1A1 2831/4885KDM4E 3544/4885ATM 4303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.