Benzene

Benzene

SCHEMBL161390

CCC(=O)O.c1ccccc1

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.83
HDAC3 O15379 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
TDP1 Q9NUW8 4/20 0.47
ALDH1A1 P00352 3/20 0.47
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
AKR1B1 P15121 2/20 0.40
LDHA P00338 1/20 0.40
SRR Q9GZT4 1/20 0.40
LMNA P02545 1/20 0.40
ALKBH5 Q6P6C2 1/20 0.40
SUCNR1 Q9BXA5 1/20 0.40
EGLN1 Q9GZT9 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PPARG P37231 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL29176309 1.00 FFAR3 (0.83) FFAR3HDAC3HDAC1HDAC2HDAC8
Benzene SCHEMBL21273380 1.00 FFAR3 (0.83) FFAR3HDAC3HDAC1HDAC2HDAC8
Benzene SCHEMBL27364471 0.96 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Benzene SCHEMBL27327713 0.96 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Benzene SCHEMBL29143211 0.96 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Benzene SCHEMBL28212569 0.96 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Benzene SCHEMBL28231011 0.96 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Benzene SCHEMBL25264854 0.93 FFAR3 (0.71) FFAR3HDAC3HDAC1HDAC2HDAC8
Benzene SCHEMBL28724902 0.93 FFAR3 (0.71) FFAR3HDAC3HDAC1HDAC2HDAC8
Propionic Acid SCHEMBL11661434 0.91 FFAR3 (1.00) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 507 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119998382-A Flame retardant compositions comprising polycycloolefinic polymers containing olefinic functionality for forming low loss films with improved dielectric and thermal properties 普罗米鲁斯有限责任公司 2025-05-13 CN claimed
CN-119890264-A Negative electrode material of lithium ion battery, preparation method of negative electrode material and battery 贝特瑞新材料集团股份有限公司 2025-04-25 CN claimed
CN-119890265-A Negative electrode material of lithium ion battery, preparation method of negative electrode material and battery 贝特瑞新材料集团股份有限公司 2025-04-25 CN claimed
CN-118955509-B Targeting near infrared fluorescent compound and preparation method and application thereof 南京诺源医疗器械有限公司 2025-03-04 CN claimed
CN-119092691-B Negative electrode material, preparation method thereof and battery 贝特瑞新材料集团股份有限公司 2025-02-18 CN claimed
CN-118652257-B Targeting near infrared fluorescent compound and preparation method and application thereof 南京诺源医疗器械有限公司 2024-12-31 CN claimed
CN-119092691-A Negative electrode material, preparation method thereof and battery 贝特瑞新材料集团股份有限公司 2024-12-06 CN claimed
CN-118955509-A Targeting near infrared fluorescent compound and preparation method and application thereof 南京诺源医疗器械有限公司 2024-11-15 CN claimed
CN-116178700-B PEGylated indocyanine dye coupled taxol prodrug type compound and preparation and application thereof 沈阳药科大学 2024-11-01 CN claimed
CN-118652257-A Targeting near infrared fluorescent compound and preparation method and application thereof 南京诺源医疗器械有限公司 2024-09-17 CN claimed
US-20040023890-A1 Drugs for diabetes NICOX S.A. (FR) 2004-02-05 US claimed
EP-1324974-A2 DRUGS FOR DIABETES Nicox S.A. (FR) 2003-07-09 EP claimed
WO-2002030867-A2 DRUGS FOR DIABETES NICOX S.A. (FR) 2002-04-18 WO claimed
EP-0856035-B1 NON-YELLOWING TAPE ARTICLE MINNESOTA MINING & MFG (US) 2000-03-01 EP claimed
WO-1999019397-A1 STABILIZED POLYOLEFIN DSM N.V. (NL) 1999-04-22 WO claimed
EP-0909797-A1 Stabilizers for vinyl ether-based coating systems AlliedSignal Inc. (US) 1999-04-21 EP claimed
EP-0636654-B1 Block copolymer composition, a process for its preparation and a hot melt adhesive comprising said composition SHELL INT RESEARCH (NL) 1997-10-01 EP claimed
EP-0773977-A1 COUPLING AGENTS FOR VINYL ETHER-BASED COATING SYSTEMS AlliedSignal Inc. (US) 1997-05-21 EP claimed
US-5491178-A STABILIZING, INHIBITING THE DEHYDROGENATION BY APPLYING A COATING MIXTURE COMPRISING HINDERED PHENOLS, ORGANIC SULFIDES OR DISULFIDES AND TRANSITION METAL SALTS OR COMPLEXES ALLIEDSIGNAL INC. (US) 1996-02-13 US claimed
WO-1996002596-A1 COUPLING AGENTS FOR VINYL ETHER-BASED COATING SYSTEMS ALLIEDSIGNAL INC. (US) 1996-02-01 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040023890-A1 Drugs for diabetes SLC5A2, ADORA2B, UGT2B7 FFAR3 1232/4885HDAC3 1794/4885HDAC1 1595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.