Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL28578 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL724028 | 1.00 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL7522896 | 1.00 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL3535 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL55583 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL29873191 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL15864609 | 1.00 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL25230484 | 0.95 | — | — | |
| Propylene Glycol SCHEMBL9240018 | 0.95 | — | — | |
| Propylene Glycol SCHEMBL11347249 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 501 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980327-A | Specific coupling of antibodies | 杭州多禧生物科技有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-114040781-A | Formulation of conjugate of TUBULYSIN derivative and cell binding molecule | 杭州多禧生物科技有限公司 | 2022-02-11 | — | — | CN | claimed |
| CN-107523018-A | A kind of preparation method for the non-toxic herb glue for being applied to slipmat surface | 安徽智博新材料科技有限公司 | 2017-12-29 | — | — | CN | claimed |
| CN-106900760-A | A kind of plant mosquito repellent liquid | 威海中玻民用新能源科技有限公司 | 2017-06-30 | — | — | CN | claimed |
| CN-105670481-A | Preparation method of water-based wood grain silicone-acrylate court material | 林宏业 | 2016-06-15 | — | — | CN | claimed |
| US-8597419-B2 | Preservative compositions for wood and like materials | GENICS INC. (CA) | 2013-12-03 | — | — | US | claimed |
| US-20100062166-A1 | PRESERVATIVE COMPOSITIONS FOR WOOD AND LIKE MATERIALS | GENICS INC. (CA) | 2010-03-11 | — | — | US | claimed |
| US-20040209790-A1 | Process and composition for cleaning medical instruments | NOVAPHARM RESEARCH (AUSTRALIA) PTY LTD (AU) | 2004-10-21 | — | — | US | claimed |
| US-6762161-B2 | SINGLE STEP HOSPITAL GRADE DISINFECTION IN SOLUTION WITH A PROTEASE, STABILIZED BY AN ACTIVITY PROTECTOR, NOT IRREVERSIBLY DENATURED; BIOCIDAL ACTIVITY; BORON ANIONS, BORIC ACID, SODIUM TETRABORATE | NOVAPHARM RESEARCH (AUSTRALIA) PTY LTD (AU) | 2004-07-13 | — | — | US | claimed |
| US-20040029752-A1 | Process and composition for cleaning medical instruments | NOVAPHARM RESEARCH (AUSTRALIA) PTY LTD (AU) | 2004-02-12 | — | — | US | claimed |
| US-20030165402-A1 | Biocidal protection system | NOVAPHARM RESEARCH (AUSTRALIA) PTY LTD. (AU) | 2003-09-04 | — | — | US | claimed |
| EP-1227926-B1 | RAPID-PROTOTYPING METHOD AND APPARATUS | GENERIS GMBH (DE) | 2003-05-14 | — | — | EP | claimed |
| EP-1137431-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING INSULIN | Provalis UK Limited (GB) | 2001-10-04 | — | — | EP | claimed |
| WO-2000033866-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING INSULIN | PROVALIS UK LIMITED (GB) | 2000-06-15 | — | — | WO | claimed |
| CN-118215676-A | Specific conjugation of antibody drug conjugates | 杭州多禧生物科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| US-20240151163-A1 | METHOD TO MAXIMIZE ENERGY RECOVERY IN WASTE-TO-ENERGY PROCESSES | PYROGENESIS CANADA INC. (CA) | 2024-05-09 | — | — | US | disclosed |
| CN-117980327-A | Specific coupling of antibodies | 杭州多禧生物科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-1057971-A | The common sulphating method of ethoxylated alcohol and unsaturated fatty alcohol | PROCTER & GAMBLE (US) | 1992-01-22 | — | — | CN | disclosed |
| CN-1034572-A | LOW-CALORIFIC AND NON-DIGESTIVE SUBSTITUTE OF FAT | ALCO CHEMICAL CORP (US) | 1989-08-09 | — | — | CN | disclosed |
| CN-87105965-A | Ion pair complex modulators and compositions thereof | — | 1988-07-06 | — | — | CN | disclosed |