Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL161401 | 1.00 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL28578 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL724028 | 1.00 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL3535 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL55583 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL29873191 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL15864609 | 1.00 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL25230484 | 0.95 | — | — | |
| Propylene Glycol SCHEMBL9240018 | 0.95 | — | — | |
| Propylene Glycol SCHEMBL11347249 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020035053-A1 | CLEAR LIQUID FABRIC SOFTENING COMPOSITIONS | PROCTER & GAMBLE COMPANY, THE | 2002-03-21 | — | — | US | disclosed |
| EP-1009788-A1 | CLEAR LIQUID FABRIC SOFTENING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999009122-A1 | CLEAR LIQUID FABRIC SOFTENING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1999-02-25 | — | — | WO | disclosed |