SCHEMBL16140269

SCHEMBL16140269

COc1cc(C)cc(C2=C(c3cc(C)cc(OC)c3)C(c3cc(C)cc(OC)c3)=C2c2cc(C)cc(OC)c2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
ACHE P22303 3/20 0.44
CYP1A1 P04798 5/20 0.43
CYP1B1 Q16678 5/20 0.43
CYP3A4 P08684 3/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2E1 P05181 2/20 0.43
CYP2C8 P10632 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2A6 P11509 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP4B1 P13584 2/20 0.43
CYP2B6 P20813 2/20 0.43
CYP3A5 P20815 2/20 0.43
CYP2A7 P20853 2/20 0.43
CYP3A7 P24462 2/20 0.43
CYP2F1 P24903 2/20 0.43
CYP2C18 P33260 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP2J2 P51589 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2952197 0.90 ALDH1A1 (0.53) ALDH1A1ACHECYP1A1CYP1B1CYP3A4
SCHEMBL145855 0.81 ALDH1A1 (0.62) ALDH1A1ACHECYP1A1CYP1B1CYP3A4
SCHEMBL12501 0.81 ALDH1A1 (0.73) ALDH1A1ACHECYP1A1CYP1B1CYP3A4
SCHEMBL29587173 0.78 ALDH1A1 (0.59) ALDH1A1ACHECYP1A1CYP1B1CYP3A4
SCHEMBL7241617 0.78 CYP1A1 (0.57) ALDH1A1ACHECYP1A1CYP1B1CYP3A4
SCHEMBL29698794 0.78 CYP1A1 (0.57) ALDH1A1ACHECYP1A1CYP1B1CYP3A4
SCHEMBL7590401 0.75 ALDH1A1 (0.48) ALDH1A1ACHECYP1A1CYP1B1CYP3A4
SCHEMBL388119 0.75 ALDH1A1 (0.48) ALDH1A1ACHECYP1A1CYP1B1CYP3A4
SCHEMBL21586162 0.74 ABL1 (0.50) ACHECYP1A1CYP1B1CYP3A4CYP1A2
SCHEMBL28533081 0.74 ABL1 (0.50) ALDH1A1ACHECYP1A1CYP1B1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140290745-A1 USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) 2014-10-02 US disclosed