Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19100214 | 0.98 | TSHR (0.40) | TSHRCYP2C19ACP3CFTRHDAC9 | |
| SCHEMBL7796898 | 0.77 | ACP3 (0.41) | ACP3CFTRHDAC9CA2CA4 | |
| SCHEMBL28428925 | 0.74 | SRC (0.36) | ACP3HDAC9CA2CA4CA5A | |
| SCHEMBL5065200 | 0.73 | MEN1 (0.34) | CYP2C19ACP3MEN1ALDH1A1KMT2A | |
| SCHEMBL15019278 | 0.68 | TSHR (0.38) | TSHRHDAC9CYP1A2 | |
| Phosphoramidic Acid SCHEMBL2479340 | 0.67 | CYP1A2 (0.48) | TSHRACP3CA2CA4CA5A | |
| SCHEMBL122942 | 0.67 | HDAC9 (0.44) | HDAC9CXCR5DPP9DPP7GRM4 | |
| SCHEMBL29476532 | 0.67 | HDAC9 (0.44) | HDAC9CXCR5DPP9DPP7GRM4 | |
| SCHEMBL13620657 | 0.67 | HDAC9 (0.40) | TSHRCYP2C19HDAC9ALDH1A1PARP1 | |
| SCHEMBL24177272 | 0.66 | CXCR5 (0.36) | ACP3HDAC9CXCR5MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104357480-B | Turn the method that RgPAL1 genes improve acteoside content in glutinous rehmannia | 安徽工业大学 | 2017-09-19 | — | — | CN | disclosed |
| CN-104357480-A | Method for improving content of verbascoside in rehmannia by virtue of transformation of RgPAL1 gene | UNIV ANHUI TECHNOLOGY | 2015-02-18 | — | — | CN | disclosed |
| US-20130017582-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON HOLDINGS, LLC (US) | 2013-01-17 | — | — | US | disclosed |
| US-8338143-B2 | Enhanced production of paclitaxel and taxanes by cell cultures of Taxus species | PHYTON HOLDINGS, LLC (US) | 2012-12-25 | — | — | US | disclosed |
| US-20110185456-A1 | Annotatd plant genes | CHEIKH NORDINE | 2011-07-28 | — | — | US | disclosed |
| US-20110086397-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON HOLDINGS, LLC (US) | 2011-04-14 | — | — | US | disclosed |
| CN-101421392-A | Use of indanoyl amide to stimulate secondary metabolism in taxus sp | PHYTON BIOTECH INC (US) | 2009-04-29 | — | — | CN | disclosed |
| US-20090011400-A1 | Substrate switched ammonia lyases and mutases | The Salk Institute for Biological Studies and The Regents of the University of California | 2009-01-08 | — | — | US | disclosed |
| WO-2008069958-A2 | SUBSTRATE SWITCHED AMMONIA LYASES AND MUTASES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2008-06-12 | — | — | WO | disclosed |
| US-20080108115-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | DFB BIOTECH, INCORPORATED (US) | 2008-05-08 | — | — | US | disclosed |
| EP-0954596-B1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON INC (US) | 2006-01-04 | — | — | EP | disclosed |
| US-20050221456-A1 | Use of indanoyl amide to stimulate secondary metabolism in Taxus sp. | PHYTON BIOTECH, INC. (US) | 2005-10-06 | — | — | US | disclosed |
| EP-1538214-A1 | Enhanced production of taxanes by cell cultures of taxus species | PHYTON, INC. (US) | 2005-06-08 | — | — | EP | disclosed |
| US-6897357-B2 | Characterization of phenylalanine ammonia-lyase (PAL) gene in wounded lettuce tissue | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-05-24 | — | — | US | disclosed |
| EP-1398384-A1 | Enhanced production of taxanes by cell cultures of taxus species | Phyton Inc. (US) | 2004-03-17 | — | — | EP | disclosed |
| US-20020173633-A1 | Characterization of phenylalanine ammonia-lyase (PAL) gene in wounded lettuce tissue | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-11-21 | — | — | US | disclosed |
| WO-2002026028-A2 | CHARACTERIZATION OF PHENYLALANINE AMMONIA-LYASE (PAL) GENE IN WOUNDED LETTUCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-04-04 | — | — | WO | disclosed |
| US-6113958-A | HEAT SHOCKING; INHIBITION OF WOUND-INDUCED ENZYME PRODUCTION; LETTUCE STORAGE STABILITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0954596-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES | PHYTON, INC. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1997044476-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON, INC. (US) | 1997-11-27 | — | — | WO | disclosed |