Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 17/20 | 0.59 |
| ▸ | PLG | P00747 | 15/20 | 0.59 |
| ▸ | PLAT | P00750 | 15/20 | 0.59 |
| ▸ | F2 | P00734 | 14/20 | 0.59 |
| ▸ | F10 | P00742 | 6/20 | 0.53 |
| ▸ | KLK8 | O60259 | 3/20 | 0.53 |
| ▸ | KLK4 | Q9Y5K2 | 3/20 | 0.53 |
| ▸ | KLK2 | P20151 | 2/20 | 0.53 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL13737965 | 0.99 | PLAU (0.58) | PLAUPLGPLATF2F10 | |
| SCHEMBL12354633 | 0.91 | PLAU (0.69) | PLAUPLGPLATF2F10 | |
| SCHEMBL2247031 | 0.90 | PLAU (0.69) | PLAUPLGPLATF2F10 | |
| SCHEMBL16144201 | 0.90 | PLAU (0.63) | PLAUPLGPLATF2F10 | |
| SCHEMBL2245991 | 0.90 | PLAU (0.71) | PLAUPLGPLATF2F10 | |
| SCHEMBL12354638 | 0.89 | PLAU (0.55) | PLAUPLGPLATF2F10 | |
| SCHEMBL17126273 | 0.87 | PLAU (0.78) | PLAUPLGPLATF2F10 | |
| SCHEMBL12354634 | 0.87 | PLAU (0.56) | PLAUPLGPLATF2F10 | |
| SCHEMBL12363216 | 0.87 | PLAU (0.52) | PLAUPLGPLATF2F10 | |
| SCHEMBL13895455 | 0.84 | PLAU (0.55) | PLAUPLGPLATF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940856-B1 | NOVEL UROKINASE INHIBITORS | UNIV ANTWERPEN (BE) | 2014-10-08 | — | — | EP | claimed |