Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 13/20 | 0.63 |
| ▸ | PLG | P00747 | 12/20 | 0.63 |
| ▸ | PLAT | P00750 | 12/20 | 0.63 |
| ▸ | F2 | P00734 | 11/20 | 0.63 |
| ▸ | F10 | P00742 | 4/20 | 0.63 |
| ▸ | KLK8 | O60259 | 2/20 | 0.43 |
| ▸ | KLK2 | P20151 | 2/20 | 0.43 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2242396 | 0.91 | PLAU (0.77) | PLAUPLGPLATF2F10 | |
| SCHEMBL16144116 | 0.90 | PLAU (0.59) | PLAUPLGPLATF2F10 | |
| Hydrochloric Acid SCHEMBL13737965 | 0.89 | PLAU (0.58) | PLAUPLGPLATF2F10 | |
| SCHEMBL12354633 | 0.88 | PLAU (0.69) | PLAUPLGPLATF2F10 | |
| SCHEMBL2242610 | 0.86 | F2 (0.79) | PLAUPLGPLATF2F10 | |
| SCHEMBL2243330 | 0.85 | PLAU (0.77) | PLAUPLGPLATF2F10 | |
| SCHEMBL2243171 | 0.84 | PLAU (0.57) | PLAUPLGPLATF2F10 | |
| SCHEMBL13740229 | 0.83 | PLAU (0.59) | PLAUPLGPLATF2F10 | |
| SCHEMBL2247031 | 0.83 | PLAU (0.69) | PLAUPLGPLATF2F10 | |
| SCHEMBL2245991 | 0.82 | PLAU (0.71) | PLAUPLGPLATF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940856-B1 | NOVEL UROKINASE INHIBITORS | UNIV ANTWERPEN (BE) | 2014-10-08 | — | — | EP | claimed |