Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18553102 | 0.76 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTPOLBLMNA | |
| SCHEMBL4199211 | 0.76 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTLMNADPP4 | |
| SCHEMBL9762149 | 0.76 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTPOLBLMNA | |
| SCHEMBL9487264 | 0.76 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTPOLBLMNA | |
| SCHEMBL10645801 | 0.76 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTPOLBLMNA | |
| SCHEMBL1683063 | 0.74 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2MAPTPOLBLMNA | |
| SCHEMBL7023419 | 0.73 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTPOLBLMNA | |
| SCHEMBL12588884 | 0.71 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2MAPTPOLBLMNA | |
| Methyl Alcohol SCHEMBL11376423 | 0.71 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTPOLBLMNA | |
| Acetic Acid SCHEMBL28866515 | 0.71 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2MAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1512397-B1 | O-SUBSTITUTED HYDROXYARYL DERIVATIVES | INST MED MOLECULAR DESIGN INC (JP) | 2014-10-08 | — | — | EP | claimed |