Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16107621 | 0.89 | ALDH1A1 (0.46) | ALDH1A1TYMP | |
| SCHEMBL16144282 | 0.79 | PDE4D (0.34) | TYMP | |
| SCHEMBL16144259 | 0.75 | P2RY14 (0.36) | TYMP | |
| SCHEMBL16144272 | 0.74 | P2RY14 (0.41) | TYMP | |
| SCHEMBL22072423 | 0.73 | ALDH1A1 (0.61) | ALDH1A1TYMP | |
| SCHEMBL14853850 | 0.73 | ALDH1A1 (0.61) | ALDH1A1TYMP | |
| SCHEMBL16144281 | 0.72 | PDE3A (0.36) | TYMP | |
| SCHEMBL16144603 | 0.71 | TYMP (0.33) | TYMP | |
| SCHEMBL22072419 | 0.70 | TYMP (0.44) | ALDH1A1TYMPGRM2 | |
| SCHEMBL26123660 | 0.70 | GRM2 (0.31) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187515-B2 | 2′,4′-fluoro nucleosides for the treatment of HCV | IDENIX PHARMACEUTICALS LLC (US) | 2015-11-17 | — | — | US | disclosed |
| US-20140294769-A1 | 2',4'-FLUORO NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC | 2014-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140294769-A1 | 2',4'-FLUORO NUCLEOSIDES FOR THE TREATMENT OF HCV | SLC29A1, SLC28A1, SLC10A1 | ALDH1A1 132/4885TYMP 87/4885GRM2 4318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.