SCHEMBL16144309

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9906175	1.00	KMT2A (0.82)	KMT2AMEN1CASRBCL2MAPK1
	SCHEMBL4062666	1.00	KMT2A (0.82)	KMT2AMEN1CASRBCL2MAPK1
	SCHEMBL26402	0.91	MEN1 (1.00)	KMT2AMEN1CASRBCL2MAPK1
	SCHEMBL249404	0.85	KMT2A (0.55)	KMT2AMEN1MAPK1TSHRHIF1A
	SCHEMBL11511851	0.83	TSHR (0.61)	KMT2AMEN1BCL2MAPK1TSHR
	SCHEMBL2864477	0.83	TSHR (0.61)	KMT2AMEN1BCL2MAPK1TSHR
	Ammonia Solution, Strong SCHEMBL11855911	0.83	KMT2A (0.52)	KMT2AMEN1MAPK1TSHRHIF1A
	SCHEMBL11106824	0.82	MEN1 (0.82)	KMT2AMEN1CASRMAPK1TSHR
	SCHEMBL28076978	0.82	MEN1 (0.82)	KMT2AMEN1CASRBCL2MAPK1
	SCHEMBL25039218	0.81	KMT2A (0.52)	KMT2AMEN1BCL2MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.