Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 5/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16144453 | 0.91 | EGFR (0.51) | EGFRADORA2ACSF1RMAP4K4ABCG2 | |
| SCHEMBL16144390 | 0.83 | PLAU (0.34) | — | |
| SCHEMBL12575566 | 0.83 | CYP1A2 (0.33) | ERBB2 | |
| SCHEMBL16144466 | 0.83 | EGFR (0.46) | EGFRADORA2ACSF1RPIK3CDMAP4K4 | |
| SCHEMBL16144440 | 0.82 | EGFR (0.46) | EGFRCSF1RPDE5AMAP4K4ABCG2 | |
| SCHEMBL16144431 | 0.81 | ABCG2 (0.42) | EGFRADORA2AMAP4K4ABCG2CLK4 | |
| SCHEMBL16144475 | 0.81 | EGFR (0.44) | EGFRADORA2ACSF1RMAP4K4ABCG2 | |
| SCHEMBL18810724 | 0.80 | CYP1A2 (0.34) | ERBB2 | |
| SCHEMBL16144487 | 0.80 | PLG (0.31) | — | |
| SCHEMBL24251325 | 0.79 | CDK4 (0.34) | ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9583718-B2 | Pyrene-based compound and organic light-emitting diode including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-02-28 | — | — | US | disclosed |
| US-9583718-B2 | Pyrene-based compound and organic light-emitting diode including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-02-28 | — | — | US | disclosed |
| US-20140291646-A1 | PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-10-02 | — | — | US | disclosed |
| US-20140291646-A1 | PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-10-02 | — | — | US | disclosed |