SCHEMBL16144390

SCHEMBL16144390

c1ccc(-c2cc(-c3ccccc3)cc(N(c3ccccc3)c3ccc4ccc5c(N(c6ccccc6)c6nccc7ccccc67)ccc6ccc3c4c65)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 0.34
PLG P00747 1/20 0.34
KCNH2 Q12809 1/20 0.32
KDM4E B2RXH2 2/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MAPT P10636 2/20 0.32
GLA P06280 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MAPK10 P53779 1/20 0.31
GPR55 Q9Y2T6 1/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
APEX1 P27695 1/20 0.30
MAPK1 P28482 1/20 0.30
PMP22 Q01453 1/20 0.30
CYP2A6 P11509 1/20 0.30
F12 P00748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16144422 0.91 PLAU (0.36) PLAUPLGKDM4ENPC1RAB9A
SCHEMBL13320976 0.89 PLAU (0.37) PLAUPLGKDM4ENPC1RAB9A
SCHEMBL13320991 0.89 PLAU (0.37) PLAUPLGKDM4ENPC1RAB9A
SCHEMBL13320969 0.86 MAPT (0.33) PLAUPLGKDM4EMAPTKMT2A
SCHEMBL12575566 0.84 CYP1A2 (0.33)
SCHEMBL16144492 0.83
SCHEMBL16144389 0.83 EGFR (0.43)
SCHEMBL16144487 0.83 PLG (0.31) PLAUPLG
SCHEMBL16144413 0.82 CYP2A6 (0.33) PLAUMAPTLMNACYP3A4APEX1
SCHEMBL13321018 0.81 PLAU (0.41) PLAUPLGKDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9583718-B2 Pyrene-based compound and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-28 US disclosed
US-9583718-B2 Pyrene-based compound and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-28 US disclosed
US-20140291646-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-02 US disclosed
US-20140291646-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-02 US disclosed