SCHEMBL16144709

SCHEMBL16144709

Cc1ncc2ccccc2c1F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.47
KDM4E B2RXH2 1/20 0.47
CYP2A6 P11509 5/20 0.45
CYP1A2 P05177 4/20 0.42
CYP11B2 P19099 2/20 0.37
ALDH1A1 P00352 4/20 0.37
NPC1 O15118 1/20 0.35
HSD11B1 P28845 1/20 0.35
MAOA P21397 1/20 0.35
TSHR P16473 2/20 0.34
HSD17B10 Q99714 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
MAPK1 P28482 1/20 0.34
PARP1 P09874 1/20 0.34
PRKCI P41743 1/20 0.34
PDE4B Q07343 1/20 0.34
HPGD P15428 1/20 0.34
NUDT1 P36639 1/20 0.34
EGFR P00533 1/20 0.34
KDR P35968 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12258315 0.78 GPR3 (0.50) GPR3KDM4ECYP2A6CYP1A2ALDH1A1
SCHEMBL2747465 0.77 KDM4E (0.48) GPR3KDM4ECYP2A6CYP1A2ALDH1A1
SCHEMBL17942817 0.77 KDM4E (0.48) GPR3KDM4ECYP2A6CYP1A2ALDH1A1
SCHEMBL13075587 0.75 GPR3 (0.47) GPR3KDM4ECYP2A6CYP1A2ALDH1A1
SCHEMBL14970136 0.75 GPR3 (0.47) GPR3KDM4ECYP2A6CYP1A2CYP11B2
SCHEMBL1564282 0.75 KDM4E (0.47) GPR3KDM4ECYP2A6CYP1A2ALDH1A1
SCHEMBL30820060 0.75 GPR3 (0.47) GPR3KDM4ECYP2A6CYP1A2ALDH1A1
SCHEMBL112386 0.75 GPR3 (0.47) GPR3KDM4ECYP2A6CYP1A2ALDH1A1
SCHEMBL16110845 0.75 SCN9A (0.54) GPR3KDM4ECYP2A6CYP1A2ALDH1A1
SCHEMBL12526215 0.75 GPR3 (0.42) GPR3KDM4ECYP2A6CYP1A2CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9583718-B2 Pyrene-based compound and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-28 US disclosed
US-20140291646-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-02 US disclosed