SCHEMBL16144806

SCHEMBL16144806

COC(C[SiH3])(OC)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.42
MAPK1 P28482 1/20 0.39
CES1 P23141 1/20 0.38
ALDH1A1 P00352 3/20 0.37
TAAR1 Q96RJ0 1/20 0.37
ALOX15 P16050 1/20 0.37
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
CYP3A4 P08684 1/20 0.35
GAA P10253 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
LMNA P02545 1/20 0.34
KIF11 P52732 2/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8072762 0.79 KCNN4 (0.43) KCNN4MAPK1CES1ALDH1A1TAAR1
SCHEMBL11409113 0.79 KCNN4 (0.43) KCNN4MAPK1CES1ALDH1A1TAAR1
SCHEMBL1225535 0.78 CES1 (0.40) KCNN4MAPK1CES1ALDH1A1TAAR1
SCHEMBL479127 0.78 KCNN4 (0.38) KCNN4MAPK1ALDH1A1TAAR1ALOX15
SCHEMBL27986959 0.77 KCNN4 (0.42) KCNN4MAPK1CES1ALDH1A1TAAR1
SCHEMBL6293779 0.77 KCNN4 (0.42) KCNN4MAPK1CES1ALDH1A1TAAR1
SCHEMBL5643547 0.77 KCNN4 (0.42) KCNN4MAPK1CES1ALDH1A1TAAR1
SCHEMBL670714 0.77 KCNN4 (0.47) KCNN4MAPK1CES1ALDH1A1TAAR1
SCHEMBL2252740 0.77 TAAR1 (0.52) KCNN4MAPK1CES1TAAR1KIF11
SCHEMBL9187550 0.76 KCNN4 (0.41) KCNN4MAPK1CES1ALDH1A1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9181399-B2 Method for producing polysiloxane TOAGOSEI CO., LTD. (JP) 2015-11-10 US claimed
US-20140323677-A1 THERMAL-SHOCK-RESISTANT CURED PRODUCT AND METHOD FOR PRODUCING SAME TOAGOSEI CO., LTD. (JP) 2014-10-30 US claimed
US-20140303392-A1 METHOD FOR PRODUCING POLYSILOXANE TOAGOSEI CO., LTD. (JP) 2014-10-09 US claimed
WO-2026105442-A1 COATING FILM, ELECTRONIC DEVICE, MOBILE BODY, AND COATING LIQUID ハドラスホールディングス株式会社 2026-05-21 WO disclosed
EP-4711423-A1 COATING FILM Hardolass Holdings Co.,Ltd. (JP) 2026-03-18 EP disclosed
WO-2025074948-A1 COATING FILM ハドラスホールディングス株式会社 2025-04-10 WO disclosed
WO-2024257682-A1 COATING METHOD AND PAINTING METHOD ハドラスホールディングス株式会社 2024-12-19 WO disclosed
WO-2024253089-A1 INORGANIC COATING FILM AND COATING LIQUID ハドラスホールディングス株式会社 2024-12-12 WO disclosed
WO-2024253090-A1 ORGANIC/INORGANIC HYBRID COATING FILM AND COATING LIQUID ハドラスホールディングス株式会社 2024-12-12 WO disclosed
US-20240158904-A1 UNDERCOAT AGENT COMPOSITION FOR LAYERING INORGANIC MATERIAL LAYER, CURED PRODUCT THEREOF AND PRODUCTION METHOD THEREOF TOAGOSEI CO., LTD. (JP) 2024-05-16 US disclosed
US-11981828-B2 Water repellent and oil repellent film composition and use thereof TOAGOSEI CO. LTD. (JP) 2024-05-14 US disclosed
US-20230128852-A1 SILSESQUIOXANE DERIVATIVE AND USE THEREOF TOAGOSEI CO., LTD. (JP) 2023-04-27 US disclosed
WO-2022168804-A1 UNDERCOAT AGENT COMPOSITION FOR INORGANIC SUBSTANCE LAYER LAMINATION, CURED PRODUCT THEREOF, AND METHOD FOR PRODUCING SAME 東亞合成株式会社 2022-08-11 WO disclosed
WO-2021153683-A1 SILSESQUIOXANE DERIVATIVE AND USE THEREFOR 東亞合成株式会社 2021-08-05 WO disclosed
US-20210238445-A1 WATER REPELLENT AND OIL REPELLENT FILM COMPOSITION AND USE THEREOF TOAGOSEI CO. LTD. (JP) 2021-08-05 US disclosed
US-9663598-B2 Organosilicon compound-containing thermosetting composition and cured product thereof TOAGOSEI CO., LTD. (JP) 2017-05-30 US disclosed
US-20160200842-A1 ORGANOSILICON COMPOUND-CONTAINING THERMOSETTING COMPOSITION AND CURED PRODUCT THEREOF TOAGOSEI CO., LTD. (JP) 2016-07-14 US disclosed
US-9181399-B2 Method for producing polysiloxane TOAGOSEI CO., LTD. (JP) 2015-11-10 US disclosed
US-20140323677-A1 THERMAL-SHOCK-RESISTANT CURED PRODUCT AND METHOD FOR PRODUCING SAME TOAGOSEI CO., LTD. (JP) 2014-10-30 US disclosed
US-20140303392-A1 METHOD FOR PRODUCING POLYSILOXANE TOAGOSEI CO., LTD. (JP) 2014-10-09 US disclosed