SCHEMBL1225535

SCHEMBL1225535

COC(CO[SiH3])(OC)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.40
KCNN4 O15554 4/20 0.39
MAPK1 P28482 1/20 0.37
ALDH1A1 P00352 2/20 0.34
TAAR1 Q96RJ0 1/20 0.34
ALOX15 P16050 1/20 0.34
GAA P10253 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.33
KIF11 P52732 2/20 0.32
KCNH2 Q12809 1/20 0.32
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6293779 0.83 KCNN4 (0.42) CES1KCNN4MAPK1ALDH1A1TAAR1
SCHEMBL5701845 0.79 MAPK1 (0.33) CES1KCNN4MAPK1ALDH1A1TAAR1
SCHEMBL5701579 0.79 MAPK1 (0.33) CES1KCNN4MAPK1ALDH1A1TAAR1
SCHEMBL16144806 0.78 KCNN4 (0.42) CES1KCNN4MAPK1ALDH1A1TAAR1
SCHEMBL5701595 0.76 KCNN4 (0.32) KCNN4MAPK1ALDH1A1
SCHEMBL8072762 0.76 KCNN4 (0.43) CES1KCNN4MAPK1ALDH1A1TAAR1
SCHEMBL11409113 0.76 KCNN4 (0.43) CES1KCNN4MAPK1ALDH1A1TAAR1
SCHEMBL5643547 0.74 KCNN4 (0.42) CES1KCNN4MAPK1ALDH1A1TAAR1
SCHEMBL705543 0.74 MAPK1 (0.44) KCNN4MAPK1ALDH1A1TAAR1ALOX15
SCHEMBL109031 0.74 TAAR1 (0.52) KCNN4MAPK1ALDH1A1TAAR1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US claimed
EP-3864059-B1 MODIFIED DIENE COPOLYMERS WITH TARGETED AND STABILIZED VISCOSITY FIRESTONE POLYMERS LLC (US) 2026-01-14 EP disclosed
US-20250179221-A1 HIGHLY FUNCTIONALIZED STABLE HYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2025-06-05 US disclosed
US-20250092168-A1 HIGHLY FUNCTIONALIZED STABLE DIHYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2025-03-20 US disclosed
EP-4460537-A1 HIGHLY FUNCTIONALIZED STABLE DIHYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS Bridgestone Americas Tire Operations, LLC (US) 2024-11-13 EP disclosed
WO-2023158819-A1 HIGHLY FUNCTIONALIZED STABLE HYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2023-08-24 WO disclosed
WO-2023133557-A1 HIGHLY FUNCTIONALIZED STABLE DIHYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2023-07-13 WO disclosed
US-20210340286-A1 Modified Diene Copolymers With Targeted And Stabilized Viscosity FIRESTONE POLYMERS, LLC (US) 2021-11-04 US disclosed
CN-109715680-B Process for preparing high cis-1, 4-polydienes with lanthanide-based catalyst compositions 株式会社普利司通 2021-10-19 CN disclosed
US-11127952-B2 Core-shell structure and production method therefof, composition for negative electrode using the core-shell structure as negative electrode active material, negative electrode and secondary battery JNC CORPORATION (JP) 2021-09-21 US disclosed
EP-2546306-A1 CURABLE COMPOSITION, HARDENED MATERIAL, AND METHOD FOR USING CURABLE COMPOSITION LINTEC Corporation (JP) 2013-01-16 EP disclosed
US-20110288257-A1 SEALING MATERIAL FOR OPTICAL ELEMENT AND SEALED OPTICAL ELEMENT KASHIO MIKIHIRO (JP) 2011-11-24 US disclosed
US-8026332-B2 curable seals for optics comprising polysilsesquioxanes with a ladder structure, having excellent transparency, crack and heat resistance LINTEC CORPORATION (JP) 2011-09-27 US disclosed
US-20110124812-A1 FIXING MATERIAL COMPRISING SILANE COMPOUND POLYMER AND PHOTONIC DEVICE SEALED BODY LINTEC CORPORATION (JP) 2011-05-26 US disclosed
US-20110054139-A1 ADHESIVE MAINLY COMPOSED OF POLYORGANOSILOXANE COMPOUND LINTEC CORPORATION (JP) 2011-03-03 US disclosed
US-20110034659-A1 MOLDING MATERIAL COMPOSED OF POLYORGANOSILOXANE COMPOUND, SEALING MATERIAL, AND SEALED OPTICAL DEVICE LINTEC CORPORATION (JP) 2011-02-10 US disclosed
US-7723444-B2 retarding the curing of the epoxy resin by adjusting an amount of the retarder while curing in presence of a curing accelerator cation phosphorus compound; used for semiconductor encapsulation; providing latency; storage stability; resist to soldering without forming cracks by the soldering SUMITOMO BAKELITE CO., LTD. (JP) 2010-05-25 US disclosed
US-20090005530-A1 Molding material comprising polysilsesquioxane compound, sealing material, and sealed optical element LINTEC CORPORATION (JP) 2009-01-01 US disclosed
US-20080249278-A1 Sealing material for optical element and sealed optical element LINTEC CORPORATION (JP) 2008-10-09 US disclosed
US-20060189721-A1 retarding the curing of the epoxy resin by adjusting an amount of the retarder while curing in presence of a curing accelerator cation phosphorus compound; used for semiconductor encapsulation; providing latency; storage stability; resist to soldering without forming cracks by the soldering SUMITOMO BAKELITE CO., LTD. (JP) 2006-08-24 US disclosed