SCHEMBL1614489

SCHEMBL1614489

Cc1ccc(S(=O)(=O)NC(=O)Nc2ccc(S(=O)(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.83
CA12 O43570 2/20 0.70
CA1 P00915 2/20 0.70
CA2 P00918 2/20 0.70
CA4 P22748 2/20 0.70
CA6 P23280 2/20 0.70
CA5A P35218 2/20 0.70
CA7 P43166 2/20 0.70
CA9 Q16790 2/20 0.70
CA13 Q8N1Q1 2/20 0.70
CA14 Q9ULX7 2/20 0.70
TP53 P04637 1/20 0.70
PPARG P37231 1/20 0.67
RAB9A P51151 1/20 0.67
RXFP1 Q9HBX9 1/20 0.67
NR2E3 Q9Y5X4 1/20 0.67
NCOR2 Q9Y618 1/20 0.67
KMT2A Q03164 3/20 0.61
MEN1 O00255 2/20 0.61
L3MBTL1 Q9Y468 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23486695 0.94 LMNA (0.88) LMNACA12CA1CA2CA4
SCHEMBL1395600 0.94 CA12 (0.78) LMNACA12CA1CA2CA4
SCHEMBL27885 0.91 LMNA (1.00) LMNACA12CA1CA2CA4
SCHEMBL21987680 0.90 LMNA (0.81) LMNACA12CA1CA2CA4
SCHEMBL20568009 0.90 LMNA (0.81) LMNACA12CA1CA2CA4
SCHEMBL6243996 0.89 CA12 (0.85) LMNACA12CA1CA2CA4
SCHEMBL1928662 0.89 CA12 (0.85) LMNACA12CA1CA2CA4
SCHEMBL28234317 0.89 LMNA (0.67) LMNACA12CA1CA2CA4
SCHEMBL23141119 0.87 LMNA (0.86) LMNACA12CA1CA2CA4
SCHEMBL29403429 0.86 LMNA (0.84) LMNACA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8652607-B2 Image recording media and imaging layers HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2014-02-18 US claimed
CN-102077282-B Image recording media and imaging layers HEWLETT PACKARD DEVELOPMENT CO 2013-08-28 CN claimed
CN-102077282-A Image recording media and imaging layers HEWLETT PACKARD DEVELOPMENT CO 2011-05-25 CN claimed
US-20110085435-A1 IMAGE RECORDING MEDIA AND IMAGING LAYERS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2011-04-14 US claimed
WO-2009157923-A1 IMAGE RECORDING MEDIA AND IMAGING LAYERS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2009-12-30 WO claimed
US-8722167-B2 Image recording media, methods of making image recording media, imaging layers, and methods of making imaging layers HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2014-05-13 US disclosed
US-8652607-B2 Image recording media and imaging layers HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2014-02-18 US disclosed
CN-102077282-B Image recording media and imaging layers HEWLETT PACKARD DEVELOPMENT CO 2013-08-28 CN disclosed
CN-102077282-A Image recording media and imaging layers HEWLETT PACKARD DEVELOPMENT CO 2011-05-25 CN disclosed
US-20110085436-A1 IMAGE RECORDING MEDIA, METHODS OF MAKING IMAGE RECORDING MEDIA, IMAGING LAYERS, AND METHODS OF MAKING IMAGING LAYERS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2011-04-14 US disclosed
US-20110085435-A1 IMAGE RECORDING MEDIA AND IMAGING LAYERS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2011-04-14 US disclosed
WO-2009157924-A1 IMAGE RECORDING MEDIA, METHODS OF MAKING IMAGE RECORDING MEDIA, IMAGING LAYERS, AND METHODS OF MAKING IMAGING LAYERS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2009-12-30 WO disclosed
WO-2009157923-A1 IMAGE RECORDING MEDIA AND IMAGING LAYERS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2009-12-30 WO disclosed