Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 4/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 11/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16147755 | 0.91 | PPARD (0.51) | ROCK1ROCK2PPARD | |
| SCHEMBL16147569 | 0.90 | ROCK1 (0.46) | ROCK1ROCK2PPARD | |
| SCHEMBL19213390 | 0.84 | PPARD (0.49) | ROCK1ROCK2PPARD | |
| SCHEMBL19213389 | 0.84 | PPARD (0.49) | ROCK1ROCK2PPARD | |
| SCHEMBL17671401 | 0.83 | PPARD (0.47) | ROCK1ROCK2PPARD | |
| SCHEMBL17671437 | 0.83 | PPARD (0.47) | ROCK1ROCK2PPARD | |
| SCHEMBL17672153 | 0.83 | HDAC1 (0.42) | ROCK1ROCK2PPARD | |
| SCHEMBL17672043 | 0.83 | HDAC1 (0.42) | ROCK1ROCK2PPARD | |
| SCHEMBL17671855 | 0.82 | ROCK1 (0.44) | ROCK1ROCK2PPARD | |
| SCHEMBL17671974 | 0.82 | ROCK1 (0.44) | ROCK1ROCK2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981522-A1 | PPAR AGONISTS | Salk Institute for Biological Studies (US) | 2016-02-10 | — | — | EP | disclosed |
| WO-2014165827-A1 | PPAR AGONISTS | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2014-10-09 | — | — | WO | disclosed |