Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012528 | 0.88 | NR4A2 (0.54) | SLC22A6NR4A2ABCB11AMY1AGPR84 | |
| SCHEMBL9120206 | 0.88 | SLC22A6 (0.62) | SLC22A6NR4A2ABCB11GPR84F7 | |
| SCHEMBL27591784 | 0.84 | NR4A2 (0.52) | SLC22A6NR4A2ABCB11GPR84F7 | |
| SCHEMBL27920538 | 0.83 | SLC22A6 (0.64) | SLC22A6NR4A2ALDH1A1IDO1MTNR1A | |
| SCHEMBL9300226 | 0.82 | NR4A2 (0.51) | SLC22A6NR4A2GPR84F7F3 | |
| SCHEMBL5530414 | 0.81 | SLC22A6 (0.62) | SLC22A6NR4A2IDO1MTNR1AMTNR1B | |
| SCHEMBL9119246 | 0.81 | SLC22A6 (0.62) | SLC22A6AMY1AGPR84IDO1MTNR1A | |
| SCHEMBL9446758 | 0.81 | SLC22A6 (0.57) | SLC22A6NR4A2ABCB11ALDH1A1MTNR1A | |
| SCHEMBL27920534 | 0.80 | KMT2A (0.53) | SLC22A6NR4A2ALDH1A1ALOX15 | |
| SCHEMBL8581148 | 0.80 | SLC22A6 (0.60) | SLC22A6NR4A2ALDH1A1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108115-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | DFB BIOTECH, INCORPORATED (US) | 2008-05-08 | — | — | US | claimed |
| US-7264951-B1 | Enhanced production of taxol and taxanes by cell cultures of Taxus species | PHYTON, INC. (US) | 2007-09-04 | — | — | US | claimed |
| US-20220136024-A1 | PROTECTING GROUP CHEMISTRY FOR CLEAN, REDUCTANT-FREE DYEING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-05-05 | — | — | US | disclosed |
| US-11213510-B2 | Thioindirubins | CITY OF HOPE (US) | 2022-01-04 | — | — | US | disclosed |
| US-11203774-B2 | Protecting group chemistry for clean, reductant-free dyeing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-12-21 | — | — | US | disclosed |
| US-20200345693-A1 | THIOINDIRUBINS | CITY OF HOPE | 2020-11-05 | — | — | US | disclosed |
| US-20200325516-A1 | PROTECTING GROUP CHEMISTRY FOR CLEAN, REDUCTANT-FREE DYEING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-10-15 | — | — | US | disclosed |
| US-10704070-B2 | Protecting group chemistry for clean, reductant-free dyeing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-07 | — | — | US | disclosed |
| WO-2019046551-A1 | THIOINDIRUBINS | CITY OF HOPE (US) | 2019-03-07 | — | — | WO | disclosed |
| US-20180037917-A1 | PROTECTING GROUP CHEMISTRY FOR CLEAN, REDUCTANT-FREE DYEING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-08 | — | — | US | disclosed |
| US-20180037917-A1 | PROTECTING GROUP CHEMISTRY FOR CLEAN, REDUCTANT-FREE DYEING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-08 | — | — | US | disclosed |
| US-20080108115-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | DFB BIOTECH, INCORPORATED (US) | 2008-05-08 | — | — | US | disclosed |
| US-7264951-B1 | Enhanced production of taxol and taxanes by cell cultures of Taxus species | PHYTON, INC. (US) | 2007-09-04 | — | — | US | disclosed |
| EP-0954596-B1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON INC (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1538214-A1 | Enhanced production of taxanes by cell cultures of taxus species | PHYTON, INC. (US) | 2005-06-08 | — | — | EP | disclosed |
| EP-1398384-A1 | Enhanced production of taxanes by cell cultures of taxus species | Phyton Inc. (US) | 2004-03-17 | — | — | EP | disclosed |
| EP-0954596-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES | PHYTON, INC. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1997044476-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON, INC. (US) | 1997-11-27 | — | — | WO | disclosed |
| WO-1995034658-A1 | MICROBIAL PRODUCTION OF INDOLE-3-ACETIC ACIDS AND SUBSTITUTED ANALOGS THEREOF VIA FERMENTATION | GENENCOR INTERNATIONAL, INC. (US) | 1995-12-21 | — | — | WO | disclosed |
| US-5364767-A | 6-chloroindole derivatives; colorimetric and quantitative analysis | RESEARCH ORGANICS, IN. (US) | 1994-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200345693-A1 | THIOINDIRUBINS | HCCS, UGT2B7, TPMT | SLC22A6 1499/4885NR4A2 1981/4885ABCB11 1339/4885 |
| US-11213510-B2 | Thioindirubins | HCCS, UGT2B7, TPMT | SLC22A6 1499/4885NR4A2 1981/4885ABCB11 1339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.