Sugi Predict

Sugi Predict / Compounds / Glutamic Acid

Glutamic Acid

Glutamic Acid

SCHEMBL1614893

N[C@@H](CCC(=O)O)C(=O)O.O=P(O)(O)CCP(=O)(O)O

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRM8 O00222 2/20 0.72
▸ GRM6 O15303 2/20 0.72
▸ GRM7 Q14831 2/20 0.72
▸ GRM4 Q14833 2/20 0.72
▸ GRIN2D O15399 1/20 0.72
▸ GRIN3B O60391 1/20 0.72
▸ GSR P00390 1/20 0.72
▸ CYP1A2 P05177 1/20 0.72
▸ GRIK1 P39086 1/20 0.72
▸ GRM5 P41594 1/20 0.72
▸ GRIA1 P42261 1/20 0.72
▸ GRIA2 P42262 1/20 0.72
▸ GRIA3 P42263 1/20 0.72
▸ SLC1A3 P43003 1/20 0.72
▸ SLC1A2 P43004 1/20 0.72
▸ SLC1A1 P43005 1/20 0.72
▸ GRIA4 P48058 1/20 0.72
▸ GRIN1 Q05586 1/20 0.72
▸ GRIN2A Q12879 1/20 0.72
▸ GRIK2 Q13002 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL6861840 0.94 GRM8 (0.69) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL6861834 0.94 GRM8 (0.69) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1065173 0.90 GRM8 (0.82) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL49767 0.90 GRM8 (0.82) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL1614530 0.88 GRM8 (0.72) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL27732867 0.88 GRM8 (0.78) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL19717585 0.88 GRM8 (0.78) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL28656083 0.88 GRM8 (0.78) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL28078987 0.86 GRM8 (0.75) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1330824 0.85 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178792-A1 METHOD OF SCALE INHIBITION Italmatch Chemicals S.P.A. (IT) 2017-06-14 — — EP disclosed
US-9108866-B2 Method of scale inhibition ITALMATCH CHEMICALS SPA (IT) 2015-08-18 — — US disclosed
US-20130264289-A1 METHOD OF SCALE INHIBITION ITALMATCH CHEMICALS SPA (IT) 2013-10-10 — — US disclosed
US-8551931-B2 Surface treatment composition containing phosphonic acid compounds DEQUEST AG (CH) 2013-10-08 — — US disclosed
US-8461088-B2 Method of scale inhibition DEQUEST AG (CH) 2013-06-11 — — US disclosed
EP-2252679-B1 SURFACE TREATMENT COMPOSITION CONTAINING PHOSPHONIC ACID COMPOUNDS DEQUEST AG (CH) 2013-04-17 — — EP disclosed
US-20130042986-A1 METHOD FOR PULP BLEACHING DEQUEST AG (CH) 2013-02-21 — — US disclosed
EP-2534296-A1 METHOD FOR PULP BLEACHING Dequest AG (CH) 2012-12-19 — — EP disclosed
WO-2011098599-A1 METHOD FOR PULP BLEACHING DEQUEST AG (CH) 2011-08-18 — — WO disclosed
US-20110124533-A1 METHOD OF SCALE INHIBITION DEQUEST AG 2011-05-26 — — US disclosed
US-20110086791-A1 SURFACE TREATMENT COMPOSITION CONTAINING PHOSPHONIC ACID COMPOUNDS DEQUEST AG (CH) 2011-04-14 — — US disclosed
EP-2252679-A1 SURFACE TREATMENT COMPOSITION CONTAINING PHOSPHONIC ACID COMPOUNDS Dequest AG (CH) 2010-11-24 — — EP disclosed
EP-2090646-A1 Surface treatment composition containing phosphonic acid compounds Thermphos Trading GmbH (CH) 2009-08-19 — — EP disclosed
WO-2009092739-A1 SURFACE TREATMENT COMPOSITION CONTAINING PHOSPHONIC ACID COMPOUNDS THERMPHOS TRADING GMBH (CH) 2009-07-30 — — WO disclosed
EP-2057099-A2 METHOD OF SCALE INHIBITION Thermphos Trading GmbH (CH) 2009-05-13 — — EP disclosed
WO-2008017338-A2 METHOD OF SCALE INHIBITION THERMPHOS TRADING GMBH (CH) 2008-02-14 — — WO disclosed
EP-1886976-A1 Method of scale inhibition Thermphos Trading GmbH (CH) 2008-02-13 — — EP disclosed