Tyrosine

Tyrosine

SCHEMBL16149122

NCCc1ccc(O)cc1.N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.80
KDM4E B2RXH2 2/20 0.60
ALDH1A1 P00352 2/20 0.60
ADRA2A P08913 2/20 0.60
HTR1A P08908 1/20 0.60
SLC6A2 P23975 1/20 0.60
CYP2C19 P33261 1/20 0.60
HTR3A P46098 1/20 0.60
BACE1 P56817 1/20 0.60
TAAR1 Q96RJ0 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
TDP1 Q9NUW8 3/20 0.58
BLM P54132 1/20 0.58
KMT2A Q03164 1/20 0.58
PTGS1 P23219 3/20 0.58
ALPI P09923 1/20 0.58
PKM P14618 1/20 0.58
XIAP P98170 1/20 0.58
HIF1A Q16665 3/20 0.54
ALOX15 P16050 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL20238845 1.00 SLC7A5 (0.80) SLC7A5KDM4EALDH1A1ADRA2AHTR1A
Phenylalanine SCHEMBL18579922 0.95 SLC7A5 (0.73) SLC7A5KDM4EALDH1A1ADRA2AHTR1A
Dl-Phenylalanine SCHEMBL20898392 0.95 SLC7A5 (0.73) SLC7A5KDM4EALDH1A1ADRA2AHTR1A
Tyrosine SCHEMBL9636551 0.95 SLC7A5 (0.73) SLC7A5KDM4EALDH1A1ADRA2AHTR1A
SCHEMBL22828926 0.93 SLC7A5 (0.67) SLC7A5KDM4EALDH1A1ADRA2ATDP1
SCHEMBL22828927 0.93 SLC7A5 (0.67) SLC7A5KDM4EALDH1A1ADRA2ATDP1
SCHEMBL16584893 0.93 SLC7A5 (0.67) SLC7A5KDM4EALDH1A1ADRA2ATDP1
Tyrosine SCHEMBL1580 0.89 SLC7A5 (1.00) SLC7A5KDM4EALDH1A1ADRA2ATAAR1
Tyrosine SCHEMBL10978820 0.89 SLC7A5 (1.00) SLC7A5KDM4EALDH1A1ADRA2ATAAR1
Tyrosine SCHEMBL11676395 0.89 SLC7A5 (1.00) SLC7A5KDM4EALDH1A1ADRA2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014165618-A9 Fast Quantification of Enzyme Activity by Electroanalysis BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-12-04 WO disclosed
WO-2014165618-A1 Fast Quantification of Enzyme Activity by Electroanalysis BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-10-09 WO disclosed