SCHEMBL1615038

SCHEMBL1615038

NCC(=O)OCCCCO[SiH3]

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.43
NAAA Q02083 1/20 0.39
RAD52 P43351 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
FAAH O00519 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
DGKA P23743 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15141421 0.95 HTR2C (0.39) HTR2CNAAADGKACYP1A2
SCHEMBL6682800 0.88 HTR2C (0.50) HTR2CNAAARAD52NPSR1FAAH
Hydrochloric Acid SCHEMBL11847967 0.83 HTR2C (0.52) HTR2CNAAARAD52NPSR1FAAH
SCHEMBL5496994 0.83 HTR2C (0.45) HTR2CNAAARAD52NPSR1FAAH
SCHEMBL18249514 0.81 HTR2C (0.46) HTR2CNAAARAD52NPSR1FAAH
Hydrochloric Acid SCHEMBL28234487 0.80 HTR2C (0.44) HTR2CNAAARAD52NPSR1FAAH
Hydrochloric Acid SCHEMBL29233271 0.79 HTR2C (0.44) HTR2CNAAARAD52NPSR1FAAH
SCHEMBL27700355 0.79 HTR2C (0.44) HTR2CNAAARAD52NPSR1FAAH
SCHEMBL18295865 0.79 HTR2C (0.48) HTR2CNAAARAD52NPSR1FAAH
SCHEMBL93781 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60210855-A None JP disclosed
US-20110083607-A1 VAPOR PHASE SELF-ASSEMBLED MONOLAYER COATING APPARATUS SORONA INC. (KR) 2011-04-14 US disclosed
US-4950701-A POLYSILOXANE ADHESIVE WITH A AROMATIC AMINE PROMOTER CEMEDINE COMPANY, LTD. (JP) 1990-08-21 US disclosed
JP-S60210855-A MANUFACTURE OF SEMICONDUCTOR DEVICE HITACHI CHEM CO LTD 1985-10-23 JP disclosed