SCHEMBL6682800

SCHEMBL6682800

NCC(=O)OCCCCOC(=O)CN

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.50
NAAA Q02083 1/20 0.46
RAD52 P43351 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 2/20 0.39
TSHR P16473 2/20 0.39
CYP3A4 P08684 1/20 0.39
FAAH O00519 1/20 0.38
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
DGKA P23743 1/20 0.36
CYP1A2 P05177 1/20 0.36
GLRA1 P23415 1/20 0.35
SLC6A9 P48067 1/20 0.35
OR51E2 Q9H255 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
HTT P42858 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA1A P35348 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11847967 0.95 HTR2C (0.52) HTR2CNAAARAD52NPSR1ALDH1A1
SCHEMBL5496994 0.94 HTR2C (0.45) HTR2CNAAARAD52NPSR1ALDH1A1
SCHEMBL18249514 0.92 HTR2C (0.46) HTR2CNAAARAD52NPSR1ALDH1A1
Hydrochloric Acid SCHEMBL28234487 0.92 HTR2C (0.44) HTR2CNAAARAD52NPSR1ALDH1A1
Hydrochloric Acid SCHEMBL29233271 0.90 HTR2C (0.44) HTR2CNAAARAD52NPSR1ALDH1A1
SCHEMBL27700355 0.90 HTR2C (0.44) HTR2CNAAARAD52NPSR1ALDH1A1
SCHEMBL18295865 0.90 HTR2C (0.48) HTR2CNAAARAD52NPSR1ALDH1A1
SCHEMBL93781 0.89
SCHEMBL38534 0.88 HTR2C (0.67) HTR2CNAAARAD52NPSR1ALDH1A1
SCHEMBL1615038 0.88 HTR2C (0.43) HTR2CNAAARAD52NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002053526-A1 NEW COMPOUNDS FOR USE AS INTERMEDIATES IN LINEAR BLOCK POLYMER AND NEW LINEAR BLOCK POLYMER ARTIMPLANT AB (SE) 2002-07-11 WO claimed
WO-2002053616-A1 NEW LINEAR BLOCK POLYMER ARTIMPLANT AB (SE) 2002-07-11 WO claimed
US-10821131-B2 Pharmaceutical formulations comprising chondroitin sulfate and hyaluronic acid derivatives FIDIA FARMACEUTICI S.P.A. (IT) 2020-11-03 US disclosed
EP-2946782-B1 PHARMACEUTICAL FORMULATIONS COMPRISING CHONDROITIN SULFATE AND HYALURONIC ACID DERIVATIVES FIDIA FARM SPA (IT) 2018-11-07 EP disclosed
US-20170216344-A1 PHARMACEUTICAL FORMULATIONS COMPRISING CHONDROITIN SULFATE AND HYALURONIC ACID DERIVATIVES FIDIA FARMACEUTICI S.P.A. (IT) 2017-08-03 US disclosed
US-9655918-B2 Pharmaceutical formulations comprising chondroitin sulfate and hyaluronic acid derivatives FIDIA FARMACEUTICI S.P.A. (IT) 2017-05-23 US disclosed
EP-2946782-A2 PHARMACEUTICAL FORMULATIONS COMPRISING CHONDROITIN SULFATE AND HYALURONIC ACID DERIVATIVES FIDIA FARMACEUTICI S.p.A. (IT) 2015-11-25 EP disclosed
US-20150072954-A1 PHARMACEUTICAL FORMULATIONS COMPRISING CHONDROITIN SULFATE AND HYALURONIC ACID DERIVATIVES FIDIA FARMACEUTICI S.P.A. (IT) 2015-03-12 US disclosed
US-6737447-B1 HIGH SURFACE AREA NANOFIBER COATINGS; MINIMIZING DEVICE PROPERTY CHANGES; DIAZENIUMDIOLATE FUNCTIONALIZED THE UNIVERSITY OF AKRON 2004-05-18 US disclosed
EP-1220694-B1 MEDICAL DEVICE COATED WITH NITRIC OXIDE-MODIFIED LINEAR POLY (ETHYLENIMINE) FIBERS AND METHOD FOR ITS MAKING UNIV AKRON (US) 2003-04-16 EP disclosed
WO-2002053526-A1 NEW COMPOUNDS FOR USE AS INTERMEDIATES IN LINEAR BLOCK POLYMER AND NEW LINEAR BLOCK POLYMER ARTIMPLANT AB (SE) 2002-07-11 WO disclosed
WO-2002053616-A1 NEW LINEAR BLOCK POLYMER ARTIMPLANT AB (SE) 2002-07-11 WO disclosed