SCHEMBL16152256

SCHEMBL16152256

COCCC#Cc1ccc(-c2c(C)c(C(=O)NN3CCCCC3)nn2-c2ccc(Cl)cc2Cl)cc1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 15/20 0.87
CNR2 P34972 3/20 0.74
CYP2C9 P11712 2/20 0.74
GPR55 Q9Y2T6 2/20 0.74
ABCC4 O15439 1/20 0.74
MLNR O43193 1/20 0.74
ABCB11 O95342 1/20 0.74
CHRM2 P08172 1/20 0.74
ADORA3 P0DMS8 1/20 0.74
ADRA2B P18089 1/20 0.74
ADRA2C P18825 1/20 0.74
DRD1 P21728 1/20 0.74
TBXA2R P21731 1/20 0.74
SLC6A2 P23975 1/20 0.74
HRH2 P25021 1/20 0.74
HTR2A P28223 1/20 0.74
AGTR1 P30556 1/20 0.74
CCKAR P32238 1/20 0.74
CCKBR P32239 1/20 0.74
MC4R P32245 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL662961 0.93 CNR1 (0.82) CNR1CNR2CYP2C9GPR55ABCC4
SCHEMBL31528987 0.92 CNR1 (1.00) CNR1CNR2CYP2C9GPR55ABCC4
SCHEMBL10138879 0.92 CNR1 (0.88) CNR1CNR2CYP2C9GPR55ABCC4
SCHEMBL2627909 0.92 CNR1 (1.00) CNR1CNR2CYP2C9GPR55ABCC4
SCHEMBL662094 0.92 CNR1 (0.81) CNR1CNR2CYP2C9GPR55ABCC4
SCHEMBL2627939 0.91 CNR1 (0.87) CNR1CNR2CYP2C9GPR55ABCC4
SCHEMBL31529028 0.91 CNR1 (0.87) CNR1CNR2CYP2C9GPR55ABCC4
SCHEMBL662749 0.91 CNR1 (0.87) CNR1CNR2CYP2C9GPR55ABCC4
SCHEMBL31529011 0.91 CNR1 (0.87) CNR1CNR2CYP2C9GPR55ABCC4
SCHEMBL14823070 0.91 CNR1 (0.87) CNR1CNR2CYP2C9GPR55ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8853205-B2 Heteropyrrole analogs acting on cannabinoid receptors UNIVERSITY OF CONNECTICUT (US) 2014-10-07 US disclosed