Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.82 |
| ▸ | CNR2 | P34972 | 3/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | MLNR | O43193 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.70 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.70 |
| ▸ | DRD1 | P21728 | 1/20 | 0.70 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | HRH2 | P25021 | 1/20 | 0.70 |
| ▸ | HTR2A | P28223 | 1/20 | 0.70 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.70 |
| ▸ | CCKAR | P32238 | 1/20 | 0.70 |
| ▸ | CCKBR | P32239 | 1/20 | 0.70 |
| ▸ | MC4R | P32245 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29471328 | 0.94 | CNR1 (0.80) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL662960 | 0.94 | CNR1 (0.80) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL16152256 | 0.93 | CNR1 (0.87) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL662094 | 0.91 | CNR1 (0.81) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL662749 | 0.90 | CNR1 (0.87) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL31529035 | 0.90 | CNR1 (0.76) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL16136717 | 0.90 | CNR1 (0.68) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL2627909 | 0.89 | CNR1 (1.00) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL10138879 | 0.89 | CNR1 (0.88) | CNR1CNR2CYP2C9GPR55ABCC4 | |
| SCHEMBL31528987 | 0.89 | CNR1 (1.00) | CNR1CNR2CYP2C9GPR55ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10053444-B2 | Cannabinergic nitrate esters and related analogs | UNIVERSITY OF CONNECTICUT (US) | 2018-08-21 | — | — | US | disclosed |
| US-20170001980-A9 | Novel Cannabinergic Nitrate Esters and Related Analogs | UNIVERSITY OF CONNECTICUT | 2017-01-05 | — | — | US | disclosed |
| US-20160096822-A1 | Novel Cannabinergic Nitrate Esters and Related Analogs | MAKRIYANNIS ALEXANDROS (US) | 2016-04-07 | — | — | US | disclosed |
| US-8853205-B2 | Heteropyrrole analogs acting on cannabinoid receptors | UNIVERSITY OF CONNECTICUT (US) | 2014-10-07 | — | — | US | disclosed |
| US-20120046280-A1 | NOVEL HETEROPYRROLE ANALOGS ACTING ON CANNABINOID RECEPTORS | UNIVERSITY OF CONNECTICUT | 2012-02-23 | — | — | US | disclosed |
| EP-2398323-A1 | NOVEL HETERO PYRROLE ANALOGS ACTING ON CANNAPINOID RECEPTORS | University of Connecticut (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010104488-A1 | NOVEL HETERO PYRROLE ANALOGS ACTING ON CANNAPINOID RECEPTORS | UNIVERSITY OF CONNECTICUT (US) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046280-A1 | NOVEL HETEROPYRROLE ANALOGS ACTING ON CANNABINOID RECEPTORS | CNR1, CNR2, CBR3 | CNR1 1/4885CNR2 2/4885CYP2C9 654/4885 |
| US-10053444-B2 | Cannabinergic nitrate esters and related analogs | CNR2, CNR1, NOS3 | CNR1 2/4885CNR2 1/4885CYP2C9 239/4885 |
| US-20160096822-A1 | Novel Cannabinergic Nitrate Esters and Related Analogs | CNR2, CNR1, CHRNB4 | CNR1 2/4885CNR2 1/4885CYP2C9 415/4885 |
| US-20170001980-A9 | Novel Cannabinergic Nitrate Esters and Related Analogs | CNR2, CNR1, CHRNB4 | CNR1 2/4885CNR2 1/4885CYP2C9 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.