Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 6/20 | 0.60 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.56 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PLEC | Q15149 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15298994 | 0.94 | USP2 (0.58) | USP2L3MBTL1CA9ALBFOLH1 | |
| SCHEMBL12464671 | 0.92 | USP2 (0.61) | USP2L3MBTL1CA9ALBFOLH1 | |
| SCHEMBL9906230 | 0.92 | USP2 (0.66) | USP2L3MBTL1CA9ALBFOLH1 | |
| SCHEMBL23258882 | 0.92 | USP2 (0.63) | USP2L3MBTL1CA9ALBFOLH1 | |
| SCHEMBL15143443 | 0.92 | USP2 (0.63) | USP2L3MBTL1CA9ALBFOLH1 | |
| SCHEMBL15143488 | 0.91 | USP2 (0.62) | USP2L3MBTL1CA9ALBFOLH1 | |
| SCHEMBL12464765 | 0.91 | USP2 (0.62) | USP2L3MBTL1CA9ALBFOLH1 | |
| SCHEMBL15717108 | 0.90 | USP2 (0.61) | USP2L3MBTL1CA9ALBFOLH1 | |
| SCHEMBL10153957 | 0.90 | USP2 (0.66) | USP2L3MBTL1CA9ALBFOLH1 | |
| SCHEMBL13287065 | 0.89 | USP2 (0.60) | USP2L3MBTL1CA9ALBFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1782071-B1 | COVALENT TETHERING OF FUNCTIONAL GROUPS TO PROTEINS AND SUBSTRATES THEREFOR | PROMEGA CORP (US) | 2014-10-08 | — | — | EP | disclosed |