Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 9/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 7/20 | 0.55 |
| ▸ | CA2 | P00918 | 7/20 | 0.55 |
| ▸ | CA12 | O43570 | 5/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15130552 | 0.93 | USP2 (0.62) | USP2L3MBTL1CA9MEN1ALPL | |
| SCHEMBL16153102 | 0.92 | USP2 (0.64) | USP2L3MBTL1CA9MEN1ALPL | |
| SCHEMBL12086245 | 0.91 | USP2 (0.60) | USP2L3MBTL1CA9MEN1ALPL | |
| SCHEMBL23258882 | 0.91 | USP2 (0.63) | USP2L3MBTL1CA9MEN1ALPL | |
| SCHEMBL15143443 | 0.91 | USP2 (0.63) | USP2L3MBTL1CA9MEN1ALPL | |
| SCHEMBL15143488 | 0.90 | USP2 (0.62) | USP2L3MBTL1CA9MEN1ALPL | |
| SCHEMBL12464765 | 0.90 | USP2 (0.62) | USP2L3MBTL1CA9MEN1ALPL | |
| SCHEMBL13656547 | 0.89 | USP2 (0.72) | USP2L3MBTL1CA9MEN1ALPL | |
| SCHEMBL12464671 | 0.89 | USP2 (0.61) | USP2L3MBTL1CA9MEN1ALPL | |
| SCHEMBL15717108 | 0.89 | USP2 (0.61) | USP2L3MBTL1CA9MEN1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850469-B2 | Methods of stapling and unstapling peptides and proteins | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-12-26 | — | — | US | disclosed |
| EP-1673399-B1 | DETECTING AND PROFILING MOLECULAR COMPLEXES | MONOGRAM BIOSCIENCES INC (US) | 2017-04-05 | — | — | EP | disclosed |
| US-20150376579-A1 | Methods Of Stapling And Unstapling Peptides And Proteins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-12-31 | — | — | US | disclosed |
| US-8198031-B2 | Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening | MONOGRAM BIOSCIENCES, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| EP-1540347-B1 | DETECTING RECEPTOR OLIGOMERIZATION | ACLARA BIOSCIENCES INC (US) | 2009-09-09 | — | — | EP | disclosed |
| US-20090173631-A1 | Single Cell Analysis of Membrane Molecules | ACLARA BIOSCIENCES, INC. | 2009-07-09 | — | — | US | disclosed |
| US-20090011432-A1 | Detecting and Profiling Molecular Complexes | MONOGRAM BIOSCIENCES, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| US-20080233602-A1 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. | 2008-09-25 | — | — | US | disclosed |
| US-7402397-B2 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. (US) | 2008-07-22 | — | — | US | disclosed |
| US-7255999-B2 | Detection of preferential polypetide in sample; otain sample containing preferential polyeptide, electrophorese, incubate with probe, detect signal from probe and recover polypeptide | MONOGRAM BIOSCIENCES, INC. (US) | 2007-08-14 | — | — | US | disclosed |
| US-7160735-B2 | Tagged microparticle compositions and methods | MONOGRAM BIOSCIENCES, INC. (US) | 2007-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376579-A1 | Methods Of Stapling And Unstapling Peptides And Proteins | SCLY, TST, SPPL2B | USP2 489/4885L3MBTL1 896/4885CA9 2578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.