Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 2/20 | 0.62 |
| ▸ | ITGAM | P11215 | 2/20 | 0.62 |
| ▸ | MAP3K5 | Q99683 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894013 | 0.87 | MAP3K5 (0.79) | ITGB2ITGAMMAP3K5MAPTHIF1AN | |
| SCHEMBL3894018 | 0.87 | MAP3K5 (0.79) | ITGB2ITGAMMAP3K5MAPTHIF1AN | |
| SCHEMBL13056334 | 0.87 | MAP3K5 (0.79) | ITGB2ITGAMMAP3K5MAPTHIF1AN | |
| SCHEMBL12340057 | 0.86 | ITGB2 (0.84) | ITGB2ITGAMMAP3K5MAPT | |
| SCHEMBL3893925 | 0.82 | MAP3K5 (0.79) | ITGB2ITGAMMAP3K5MAPTHIF1AN | |
| SCHEMBL3893918 | 0.82 | MAP3K5 (0.79) | ITGB2ITGAMMAP3K5MAPTHIF1AN | |
| SCHEMBL13056333 | 0.81 | MAP3K5 (0.72) | MAP3K5MAPT | |
| SCHEMBL20846475 | 0.80 | MAP3K5 (0.59) | ITGB2ITGAMMAP3K5MAPTHIF1AN | |
| SCHEMBL8290217 | 0.80 | MAP3K5 (0.76) | ITGB2ITGAMMAP3K5MAPT | |
| SCHEMBL12340045 | 0.79 | ITGB2 (0.72) | ITGB2ITGAMMAP3K5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140303026-A1 | Compounds for Modulating Integrin CD11B/CD18 | GB006, INC. | 2014-10-09 | — | — | US | disclosed |
| US-20140303026-A1 | Compounds for Modulating Integrin CD11B/CD18 | GB006, INC. | 2014-10-09 | — | — | US | disclosed |