Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.54 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.54 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.54 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.52 |
| ▸ | FLT3 | P36888 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.52 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.52 |
| ▸ | MST1R | Q04912 | 1/20 | 0.52 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.52 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16133542 | 0.92 | CLK4 (0.46) | CLK4NTRK2DYRK1BTYRO3NTRK1 | |
| SCHEMBL16135668 | 0.82 | CLK4 (0.59) | CLK4NTRK2DYRK1BTYRO3NTRK1 | |
| SCHEMBL16154658 | 0.80 | CLK4 (0.39) | CLK4NTRK2DYRK1BTYRO3NTRK1 | |
| SCHEMBL16154661 | 0.78 | CLK4 (0.49) | CLK4NTRK2DYRK1BTYRO3NTRK1 | |
| SCHEMBL23502017 | 0.75 | PRKCI (0.50) | CLK4NTRK2DYRK1BTYRO3NTRK1 | |
| SCHEMBL23137955 | 0.73 | CLK4 (0.56) | CLK4NTRK2DYRK1BTYRO3NTRK1 | |
| SCHEMBL25920352 | 0.73 | CLK4 (0.73) | CLK4NTRK2DYRK1BTYRO3NTRK1 | |
| SCHEMBL15980672 | 0.73 | CLK4 (0.51) | CLK4NTRK2DYRK1BTYRO3NTRK1 | |
| SCHEMBL16154668 | 0.72 | CLK4 (0.43) | CLK4NTRK2DYRK1BTYRO3NTRK1 | |
| SCHEMBL19187116 | 0.72 | CLK4 (0.74) | CLK4NTRK2DYRK1BTYRO3NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210009555-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2021-01-14 | — | — | US | disclosed |
| US-9951043-B2 | Therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-20140303164-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2014-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009555-A1 | THERAPEUTIC COMPOUNDS | HAVCR2, SARS1, RPL35 | CLK4 4768/4885NTRK2 4324/4885DYRK1B 4883/4885 |
| US-20140303164-A1 | THERAPEUTIC COMPOUNDS | HAVCR2, SARS1, G6PD | CLK4 4766/4885NTRK2 4438/4885DYRK1B 4883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.