Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Choline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Choline SCHEMBL27945166 | 1.00 | MEN1 (0.86) | — | |
| Choline SCHEMBL27926093 | 1.00 | MEN1 (0.86) | — | |
| Choline SCHEMBL28298124 | 0.96 | — | — | |
| Choline SCHEMBL8588331 | 0.96 | — | — | |
| Choline SCHEMBL27998285 | 0.96 | — | — | |
| Choline SCHEMBL11228907 | 0.96 | — | — | |
| Choline SCHEMBL2678893 | 0.96 | — | — | |
| Choline SCHEMBL7638167 | 0.96 | — | — | |
| Choline SCHEMBL5693169 | 0.96 | — | — | |
| Choline SCHEMBL16558587 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040359-A | Azole selenourea carboxylate and preparation method and application thereof | 华南农业大学 | 2025-05-27 | — | — | CN | claimed |
| WO-2024089683-A1 | ANTICANCER DRUG CONJUGATES | Ariel Scientific Innovations Ltd. (IL) | 2024-05-02 | — | — | WO | claimed |
| CN-117326934-A | Preparation method of 2,4-D choline amine salt aqueous solution | 威海韩孚生化药业有限公司 | 2024-01-02 | — | — | CN | claimed |
| CN-116726881-A | Amphiphilic magnetic response organic affinity adsorbent and preparation method and application thereof | 徐州工程学院 | 2023-09-12 | — | — | CN | claimed |
| EP-4005384-A1 | HERBICIDAL COMPOSITION CONTAINING R-TYPE PYRIDYLOXY CARBOXYLIC ACID DERIVATIVE AND USE THEREOF | Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) | 2022-06-01 | — | — | EP | claimed |
| EP-3904341-A1 | R-TYPE PYRIDYLOXYCARBOXYLIC ACID, SALT AND ESTER DERIVATIVE THEREOF, AND PREPARATION METHOD THEREFOR, AND HERBICIDAL COMPOSITION AND APPLICATION THEREOF | Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) | 2021-11-03 | — | — | EP | claimed |
| CN-111377856-B | R-type pyridyloxy carboxylic acid and salt and ester derivatives thereof, preparation method, herbicidal composition and application | 青岛清原化合物有限公司 | 2021-08-27 | — | — | CN | claimed |
| CN-111377856-A | R-type pyridyloxy carboxylic acid and salt and ester derivatives thereof, preparation method, herbicidal composition and application | 青岛清原化合物有限公司 | 2020-07-07 | — | — | CN | claimed |
| WO-2020135235-A1 | R-TYPE PYRIDYLOXYCARBOXYLIC ACID, SALT AND ESTER DERIVATIVE THEREOF, AND PREPARATION METHOD THEREFOR, AND HERBICIDAL COMPOSITION AND APPLICATION THEREOF | 青岛清原化合物有限公司 | 2020-07-02 | — | — | WO | claimed |
| CN-110364761-A | A kind of high-energy density long circulating ferric phosphate lithium cell | 江西省汇亿新能源有限公司 | 2019-10-22 | — | — | CN | claimed |
| CN-105374980-A | An interface infiltrated quasi-solid alkali metal cell, electrodes of the cell and a preparing method of the cell | INST PHYSICS CAS | 2016-03-02 | — | — | CN | claimed |
| CN-105037588-A | Isoindole rare earth metal catalyst, preparation method and application | BEIJING INST TECHNOLOGY | 2015-11-11 | — | — | CN | claimed |
| CN-102965082-B | Working substance pair for absorptive thermal cycling system with heat source temperature ranging from 60 to 130 DEG C | UNIV CHINA GEOSCIENCES WUHAN | 2015-03-04 | — | — | CN | claimed |
| CN-103182324-B | Preparation method of hydrophobic organic framework solid base catalyst | PETROCHINA CO LTD | 2015-01-21 | — | — | CN | claimed |
| CN-104273121-A | 2,4-dichlorophenoxy quaternary ammonium salt soluble granules and preparation method thereof | ZHEJIANG WYNCA CHEMICAL INDUSTRY GROUP CO LTD | 2015-01-14 | — | — | CN | claimed |
| CN-103182324-A | Preparation method of hydrophobic organic framework solid base catalyst | PETROCHINA CO LTD | 2013-07-03 | — | — | CN | claimed |
| CN-101218224-B | Compositions and methods for treating or preventing flavivirus infections | VIROCHEM PHARMA INC | 2013-05-08 | — | — | CN | claimed |
| CN-102718744-A | Compounds and methods for the treatment or prevention of flavivirus infections | VIROCHEM PHARMA INC | 2012-10-10 | — | — | CN | claimed |
| CN-101218224-A | Compositions and methods for treating or preventing flavivirus infections | VIROCHEM PHARMA INC (CA) | 2008-07-09 | — | — | CN | claimed |
| US-20060025458-A1 | Alkylammonium compounds as antifungal and antitrypanosomal agents | UNIVERSITY OF CONNECTICUT | 2006-02-02 | — | — | US | claimed |