SCHEMBL1615543

SCHEMBL1615543

NCCNCCC1CCCCC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.56
CA12 O43570 3/20 0.46
CA6 P23280 3/20 0.46
CA7 P43166 3/20 0.46
CA9 Q16790 3/20 0.46
CA14 Q9ULX7 3/20 0.46
CA5B Q9Y2D0 3/20 0.46
MEN1 O00255 1/20 0.46
RECQL P46063 1/20 0.46
KMT2A Q03164 1/20 0.46
LMNA P02545 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CA2 P00918 2/20 0.43
CA3 P07451 2/20 0.43
CA4 P22748 2/20 0.43
CA5A P35218 2/20 0.43
CA1 P00915 1/20 0.43
ALOX15 P16050 1/20 0.43
ALDH1A1 P00352 1/20 0.43
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6974974 0.98 SIGMAR1 (0.52) SIGMAR1CA12CA6CA7CA9
SCHEMBL6976013 0.90 SIGMAR1 (0.61) SIGMAR1CA12CA6CA7CA9
SCHEMBL20491429 0.90 SIGMAR1 (0.55) SIGMAR1CA12CA6CA7CA9
SCHEMBL18531456 0.89 SIGMAR1 (0.59) SIGMAR1CA12CA6CA7CA9
SCHEMBL21173520 0.89 SIGMAR1 (0.59) SIGMAR1CA12CA6CA7CA9
SCHEMBL23131807 0.89 SIGMAR1 (0.59) SIGMAR1CA12CA6CA7CA9
SCHEMBL18823178 0.89 SIGMAR1 (0.59) SIGMAR1CA12CA6CA7CA9
SCHEMBL5057409 0.89 SIGMAR1 (0.59) SIGMAR1CA12CA6CA7CA9
SCHEMBL6975488 0.89 SIGMAR1 (0.54) SIGMAR1CA12CA6CA7CA9
SCHEMBL18430893 0.89 SIGMAR1 (0.59) SIGMAR1CA12CA6CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338065-B2 Electrophotographic photoreceptor and image forming apparatus provided with the same SHARP KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-20110085823-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS PROVIDED WITH THE SAME SHARP KABUSHIKI KAISHA (JP) 2011-04-14 US disclosed
EP-0870765-B1 AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS ZERIA PHARM CO LTD (JP) 2003-11-19 EP disclosed
US-5981557-A HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT ZERIA PHARMACEUTICAL CO., LTD. (JP) 1999-11-09 US disclosed
EP-0870765-A1 AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS ZERIA PHARMACEUTICAL CO., LTD. (JP) 1998-10-14 EP disclosed
US-4942226-A ANTITUMOR AGENTS, RADIATION SENSITIZERS MERCK & CO., INC. (US) 1990-07-17 US disclosed