Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | RORA | P35398 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.39 |
| ▸ | RORB | Q92753 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | PGR | P06401 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15979462 | 1.00 | TDP1 (0.45) | TDP1L3MBTL1TNFADORA2BRORA | |
| SCHEMBL2418945 | 1.00 | TDP1 (0.45) | TDP1L3MBTL1TNFADORA2BRORA | |
| SCHEMBL16155984 | 1.00 | TDP1 (0.45) | TDP1L3MBTL1TNFADORA2BRORA | |
| SCHEMBL15277852 | 1.00 | TDP1 (0.45) | TDP1L3MBTL1TNFADORA2BRORA | |
| SCHEMBL13558215 | 0.92 | RORA (0.41) | TDP1L3MBTL1TNFADORA2BRORA | |
| SCHEMBL12295134 | 0.84 | TDP1 (0.38) | TDP1L3MBTL1TNFADORA2BRORA | |
| SCHEMBL15277859 | 0.83 | TDP1 (0.41) | TDP1L3MBTL1TNFADORA2BRORA | |
| SCHEMBL15280937 | 0.82 | PTGER4 (0.32) | TDP1L3MBTL1RORARORCRORB | |
| SCHEMBL15984262 | 0.80 | SRC (0.39) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL19342531 | 0.80 | HPGD (0.36) | TDP1L3MBTL1TNFADORA2BMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859714-B1 | Polymeric semiconductors and related devices | NORTHWESTERN UNIVERSITY (US) | 2014-10-14 | — | — | US | disclosed |