Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 5/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13721336 | 0.87 | KDM4E (0.49) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL1787852 | 0.86 | HPGD (0.52) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL13721059 | 0.85 | KDM4E (0.48) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL13721152 | 0.82 | AKR1B1 (0.58) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL30824700 | 0.82 | KDM4E (0.54) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL1785726 | 0.82 | KDM4E (0.54) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL30796387 | 0.81 | TSHR (0.51) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL1788819 | 0.81 | TSHR (0.51) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL13720159 | 0.81 | KDM4E (0.51) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL1790428 | 0.81 | ADRA1A (0.51) | KDM4EHPGDMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859549-B2 | Potassium channel modulators | ABBVIE, INC. (US) | 2014-10-14 | — | — | US | claimed |
| US-8859549-B2 | Potassium channel modulators | ABBVIE, INC. (US) | 2014-10-14 | — | — | US | disclosed |