Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16156159 | 1.00 | ITGB3 (0.44) | ITGB3ITGA2BTSHRTP53PLA2G4B | |
| SCHEMBL16156099 | 1.00 | ITGB3 (0.44) | ITGB3ITGA2BTSHRTP53PLA2G4B | |
| SCHEMBL16156093 | 0.96 | ITGB3 (0.43) | ITGB3ITGA2BTSHRTP53PLA2G4B | |
| SCHEMBL16156096 | 0.96 | ITGB3 (0.43) | ITGB3ITGA2BTSHRTP53PLA2G4B | |
| SCHEMBL16156112 | 0.96 | ITGB3 (0.43) | ITGB3ITGA2BTSHRTP53PLA2G4B | |
| SCHEMBL16156092 | 0.96 | ITGB3 (0.43) | ITGB3ITGA2BTSHRTP53PLA2G4B | |
| SCHEMBL16156098 | 0.94 | ITGB3 (0.48) | ITGB3ITGA2BTSHRTP53PLA2G4B | |
| SCHEMBL14786081 | 0.93 | ITGB3 (0.42) | ITGB3ITGA2BTSHRTP53PLA2G4B | |
| SCHEMBL14784405 | 0.93 | ITGB3 (0.42) | ITGB3ITGA2BTSHRTP53PLA2G4B | |
| SCHEMBL14786104 | 0.93 | ITGB3 (0.42) | ITGB3ITGA2BTSHRTP53PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145069-A1 | GLP-1 Derivatives | NOVO NORDISK AS (DK) | 2017-05-25 | — | — | US | disclosed |
| US-20140303083-A1 | GLP-1 Derivatives | NOVO NORDISK A/S (DK) | 2014-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145069-A1 | GLP-1 Derivatives | GLP1R, GIPR, GCG | ITGB3 2649/4885ITGA2B 4558/4885TSHR 447/4885 |
| US-20140303083-A1 | GLP-1 Derivatives | GLP1R, GIPR, GCG | ITGB3 2328/4885ITGA2B 4262/4885TSHR 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.