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SCHEMBL16156153

SCHEMBL16156153

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nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NMT1 P30419 6/20 0.42
▸ NMT2 O60551 5/20 0.42
▸ TLR2 O60603 2/20 0.38
▸ OPRM1 P35372 2/20 0.34
▸ OPRD1 P41143 2/20 0.34
▸ OPRK1 P41145 1/20 0.34
▸ PRMT1 Q99873 1/20 0.33
▸ QRFPR Q96P65 1/20 0.33
▸ SIRT6 Q8N6T7 1/20 0.33
▸ SIRT1 Q96EB6 1/20 0.33
▸ SIRT5 Q9NXA8 2/20 0.32
▸ SIRT2 Q8IXJ6 1/20 0.32
▸ CD40 P25942 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18888079 0.89 NMT1 (0.42) NMT1NMT2TLR2OPRM1OPRD1
SCHEMBL16156166 0.81 NMT1 (0.39) NMT1NMT2OPRM1OPRD1OPRK1
SCHEMBL19334649 0.78 NMT1 (0.39) NMT1NMT2OPRM1OPRD1OPRK1
SCHEMBL18568961 0.78 NMT1 (0.39) NMT1NMT2OPRM1OPRD1OPRK1
SCHEMBL16156095 0.78 NMT1 (0.43) NMT1NMT2TLR2OPRM1OPRD1
SCHEMBL16314006 0.76 MME (0.45) NMT1NMT2OPRM1OPRD1OPRK1
SCHEMBL18568832 0.74 NMT1 (0.41) NMT1NMT2TLR2OPRM1OPRD1
SCHEMBL18568932 0.74 TLR2 (0.43) NMT1NMT2TLR2QRFPR
SCHEMBL19334696 0.74 TLR2 (0.43) NMT1NMT2TLR2QRFPR
SCHEMBL16156114 0.72 GLP1R (0.48) NMT1NMT2TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140303083-A1 GLP-1 Derivatives NOVO NORDISK A/S (DK) 2014-10-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140303083-A1 GLP-1 Derivatives GLP1R, GIPR, GCG NMT1 1096/4885NMT2 1365/4885TLR2 1394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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