Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | NMT2 | O60551 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16156166 | 0.86 | NMT1 (0.39) | MMEOPRM1OPRD1NMT2NMT1 | |
| SCHEMBL16313896 | 0.85 | MME (0.43) | MMETGFBR1OPRM1OPRD1NMT2 | |
| SCHEMBL19334649 | 0.83 | NMT1 (0.39) | MMEOPRM1OPRD1NMT2NMT1 | |
| SCHEMBL29447806 | 0.83 | MME (0.44) | MMETGFBR1OPRM1OPRD1NMT2 | |
| SCHEMBL18568961 | 0.83 | NMT1 (0.39) | MMEOPRM1OPRD1NMT2NMT1 | |
| SCHEMBL4083058 | 0.82 | OPRM1 (0.43) | MMETGFBR1OPRM1OPRD1NMT2 | |
| SCHEMBL4083063 | 0.82 | OPRM1 (0.43) | MMETGFBR1OPRM1OPRD1NMT2 | |
| SCHEMBL22622404 | 0.82 | TGFBR1 (0.42) | MMETGFBR1OPRM1OPRD1NMT2 | |
| SCHEMBL18568832 | 0.82 | NMT1 (0.41) | OPRM1OPRD1NMT2NMT1ALDH1A1 | |
| SCHEMBL29372719 | 0.81 | TGFBR1 (0.42) | MMETGFBR1OPRM1OPRD1NMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |