Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171576 | 0.90 | NPC1 (0.48) | CES1L3MBTL1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL16432294 | 0.87 | TLR7 (0.47) | CES1L3MBTL1SMN1; SMN2KMT2ATLR7 | |
| SCHEMBL1773218 | 0.83 | L3MBTL1 (0.52) | CES1L3MBTL1SMN1; SMN2KMT2ACETP | |
| SCHEMBL29788112 | 0.83 | L3MBTL1 (0.52) | CES1L3MBTL1SMN1; SMN2KMT2ACETP | |
| SCHEMBL12746102 | 0.79 | L3MBTL1 (0.52) | CES1L3MBTL1SMN1; SMN2CETPP4HTM | |
| SCHEMBL2396377 | 0.79 | L3MBTL1 (0.47) | CES1L3MBTL1SMN1; SMN2KMT2AP4HTM | |
| SCHEMBL2465434 | 0.78 | SMN1; SMN2 (0.50) | CES1L3MBTL1SMN1; SMN2KMT2AP4HTM | |
| SCHEMBL28807700 | 0.76 | L3MBTL1 (0.48) | CES1L3MBTL1SMN1; SMN2KMT2ACETP | |
| SCHEMBL2536278 | 0.76 | SMN1; SMN2 (0.48) | CES1L3MBTL1SMN1; SMN2KMT2ACETP | |
| SCHEMBL20135764 | 0.75 | L3MBTL1 (0.47) | CES1L3MBTL1SMN1; SMN2CETPP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598340-B2 | Metal-catalyzed coupling of aryl and vinyl halides with alpha, alpha-difluorocarbonyl compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-21 | — | — | US | disclosed |
| US-9598340-B2 | Metal-catalyzed coupling of aryl and vinyl halides with alpha, alpha-difluorocarbonyl compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-21 | — | — | US | disclosed |
| WO-2014165861-A1 | METAL-CATALYZED COUPLING OF ARYL AND VINYL HALIDES WITH ALPHA, ALPHA-DIFLUOROCARBONYL COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-10-09 | — | — | WO | disclosed |