SCHEMBL16158779

SCHEMBL16158779

c1ccc(-c2cc(-c3ccccc3)nc(-c3ccc(-c4cccc5c4ccc4c(-c6ccc(-c7cc(-c8ccccc8)cc(-c8ccccc8)n7)cc6)cccc45)cc3)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
RAB9A P51151 1/20 0.47
ACACA Q13085 2/20 0.46
DHODH Q02127 1/20 0.45
ACHE P22303 1/20 0.43
MCL1 Q07820 2/20 0.43
ENPP3 O14638 1/20 0.43
ENPP1 P22413 1/20 0.43
TNF P01375 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
CTRC Q99895 1/20 0.41
MYC P01106 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16158684 1.00 CYP19A1 (0.47) CYP19A1MEN1KMT2ARAB9AACACA
SCHEMBL16158775 0.98 CYP19A1 (0.46) CYP19A1MEN1KMT2ARAB9AACACA
SCHEMBL16158651 0.97 CYP19A1 (0.45) CYP19A1MEN1KMT2ARAB9AACACA
SCHEMBL17969931 0.96 MEN1 (0.50) CYP19A1MEN1KMT2ARAB9AACACA
SCHEMBL17970037 0.96 MEN1 (0.50) CYP19A1MEN1KMT2ARAB9AACACA
SCHEMBL23921296 0.91 ENPP3 (0.53) CYP19A1MEN1KMT2ARAB9AACACA
SCHEMBL23921298 0.91 ENPP3 (0.53) CYP19A1MEN1KMT2ARAB9AACACA
SCHEMBL16158690 0.91 CYP19A1 (0.46) CYP19A1MEN1KMT2ARAB9AACACA
SCHEMBL17829284 0.90 MEN1 (0.54) CYP19A1MEN1KMT2ARAB9AACACA
SCHEMBL17829285 0.90 MEN1 (0.54) CYP19A1MEN1KMT2ARAB9AACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2873666-B1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT CONTAINING SAME LG CHEMICAL LTD (KR) 2017-09-20 EP disclosed
US-9412954-B2 Heterocyclic compound and organic electronic element containing same LG CHEM, LTD. (KR) 2016-08-09 US disclosed
US-9412954-B2 Heterocyclic compound and organic electronic element containing same LG CHEM, LTD. (KR) 2016-08-09 US disclosed
EP-2873666-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT CONTAINING SAME LG Chem, Ltd. (KR) 2015-05-20 EP disclosed
US-20140299192-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT CONTAINING SAME LG CHEM, LTD. (KR) 2014-10-09 US disclosed
US-20140299192-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT CONTAINING SAME LG CHEM, LTD. (KR) 2014-10-09 US disclosed