Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Acetone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL3134673 | 0.88 | — | — | |
| Acetone SCHEMBL28196733 | 0.88 | — | — | |
| Acetone SCHEMBL9165062 | 0.88 | — | — | |
| Acetone SCHEMBL6926852 | 0.88 | — | — | |
| Acetone SCHEMBL11659515 | 0.88 | — | — | |
| Acetone SCHEMBL10895039 | 0.88 | — | — | |
| Acetone SCHEMBL528137 | 0.87 | LMNA (1.00) | — | |
| Acetone SCHEMBL7459124 | 0.87 | — | — | |
| Acetone SCHEMBL10051950 | 0.87 | — | — | |
| Acetone SCHEMBL10051943 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206859-B | 3-Aryloxy-3-five-membered heteroaryl-propylamine compound, and crystal forms and application thereof | 上海璃道医药科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-116143672-B | Water-soluble antioxidant and preparation method and application thereof | 卫星化学股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-112654616-B | 3-aryloxy-3-aryl-propylamines and application thereof | 漳州片仔癀药业股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-113773417-B | Alpha, alpha' -diiodo-p-xylene, hydroxyl-terminated polyacrylate polyol, polyurethane prepolymer, sealant and preparation method thereof | 广东普赛达密封粘胶有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116143672-A | Water-soluble antioxidant and preparation method and application thereof | 卫星化学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| US-20220119375-A1 | 3-ARYLOXY-3-ARYL-PROPYLAMINE COMPOUND AND USES THEREOF | ZHANGZHOU PIEN TZE HUANG PHARMACEUTICAL CO., LTD. (CN) | 2022-04-21 | — | — | US | disclosed |
| CN-113773417-A | Alpha, alpha' -diiodo-p-xylene, hydroxyl-terminated polyacrylate polyol, polyurethane prepolymer, sealant and preparation method thereof | 广东普赛达密封粘胶有限公司 | 2021-12-10 | — | — | CN | disclosed |
| US-20210332035-A1 | 3-ARYLOXYL-3-FIVE-MEMBERED HETEROARYL PROPYLAMINE COMPOUND AND USE THEREOF | SHANGHAI LEADO PHARMATECH CO. LTD. (CN) | 2021-10-28 | — | — | US | disclosed |
| EP-3838900-A1 | 3-ARYLOXY-3-ARYL-PROPYLAMINE COMPOUND AND USES THEREOF | Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd (CN) | 2021-06-23 | — | — | EP | disclosed |
| EP-3838899-A1 | 3-ARYLOXYL-3-FIVE-MEMBERED HETEROARYL PROPYLAMINE COMPOUND AND USE THEREOF | Shanghai Leado Pharmatech Co. Ltd. (CN) | 2021-06-23 | — | — | EP | disclosed |
| EP-0359400-A1 | Fungicidal benzodioxane amine derivatives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-21 | — | — | EP | disclosed |
| CN-1040371-A | The preparation method of benzo two alkanamine derivatives | DU PONT (US) | 1990-03-14 | — | — | CN | disclosed |
| WO-1990002122-A1 | FUNGICIDAL BENZODIOXANE AMINE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-08 | — | — | WO | disclosed |
| US-4794189-A | Synthesis of N-succinimidyl haloacetyl aminobenzoates | AKZO AMERICA INC. (US) | 1988-12-27 | — | — | US | disclosed |
| EP-0235301-A1 | PYRIDOPYRIMIDINE NUCLEOTIDE DERIVATIVES | TEIJIN LIMITED (JP) | 1987-09-09 | — | — | EP | disclosed |
| EP-0205326-A2 | Antibody conjugates | Immunomedics, Inc. (US) | 1986-12-17 | — | — | EP | disclosed |
| EP-0033561-B1 | NOVEL 17-AMINO-16-HYDROXY STEROIDS OF THE ANDROSTANE AND OESTRANE SERIES AND DERIVATIVES THEREOF, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | AKZO N.V. (NL) | 1983-05-11 | — | — | EP | disclosed |
| US-4330539-A | Novel 17-amino-16-hydroxy steroids of the androstane and oestrane series and derivatives thereof | AKZO NV (NL) | 1982-05-18 | — | — | US | disclosed |
| EP-0033561-A1 | Novel 17-amino-16-hydroxy steroids of the androstane and oestrane series and derivatives thereof, processes for their preparation and pharmaceutical compositions | AKZO N.V. (NL) | 1981-08-12 | — | — | EP | disclosed |
| US-4217310-A | AGAINST AUTOPEROXIDATIVE DECOMPOSITION, GLYCIDOL | PPG INDUSTRIES, INC. (US) | 1980-08-12 | — | — | US | disclosed |