Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3765360 | 0.81 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2POLBHPGDGAA | |
| SCHEMBL3759117 | 0.80 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2POLBHPGDGAA | |
| SCHEMBL3765395 | 0.72 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2POLBHPGDGAA | |
| SCHEMBL27595783 | 0.71 | NPSR1 (0.34) | — | |
| SCHEMBL3763750 | 0.69 | MAPT (0.38) | ALDH1A1SMN1; SMN2POLBHPGDKMT2A | |
| SCHEMBL161104 | 0.68 | HPGD (0.69) | ALDH1A1HPGDKMT2AKDM4ECA12 | |
| SCHEMBL11267540 | 0.68 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2POLBHPGDGAA | |
| SCHEMBL3760367 | 0.68 | MEN1 (0.36) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL20197 | 0.67 | HPGD (0.73) | ALDH1A1HPGDKMT2ACA12CA1 | |
| SCHEMBL27978775 | 0.67 | HPGD (0.73) | ALDH1A1HPGDKMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029570-B1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2014-10-15 | — | — | EP | disclosed |