Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16162143 | 0.93 | BRAF (0.58) | BRAFMAP3K20 | |
| SCHEMBL16162131 | 0.86 | BRAF (0.44) | BRAF | |
| SCHEMBL300434 | 0.85 | BRAF (0.64) | BRAF | |
| SCHEMBL16162013 | 0.84 | BRAF (0.64) | BRAF | |
| SCHEMBL16161966 | 0.84 | BRAF (0.63) | BRAF | |
| SCHEMBL16162082 | 0.83 | BRAF (0.62) | BRAFMAP3K20 | |
| SCHEMBL16162149 | 0.82 | MAP3K20 (0.44) | BRAFMAP3K20 | |
| SCHEMBL16162138 | 0.82 | BRAF (0.63) | BRAF | |
| SCHEMBL16162118 | 0.82 | CYP2C9 (0.46) | BRAF | |
| SCHEMBL16162126 | 0.82 | BRAF (0.44) | BRAFMAP3K20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170830-B1 | 2-FLUORO-BENZENESULFONAMIDE COMPOUNDS AS Raf KINASE MODULATORS | PLEXXIKON INC (US) | 2014-10-15 | — | — | EP | claimed |